{"id":"W2618844455","doi":"10.1093/ndt/gfx126","title":"MO068EFFICACY AND SAFETY OF MIGALASTAT, AN ORAL PHARMACOLOGICAL CHAPERONE FOR FABRY DISEASE: RENAL FINDINGS FROM TWO RANDOMIZED PHASE 3 STUDIES (FACETS AND ATTRACT)","year":2017,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Medicine; Fabry disease; Kidney disease; Intensive care medicine; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004685741,0.001405769,0.002628403,0.0004122566,0.000456986,0.001114064,0.00080247,0.001904106,0.004517364],"category_scores_gemma":[0.002422926,0.0006035595,0.002494305,0.000435935,0.001123847,0.0009516149,0.000420988,0.002035785,0.0006258237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008830148,"about_ca_system_score_gemma":0.001349385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009241086,"about_ca_topic_score_gemma":0.002457594,"domain_scores_codex":[0.9983852,0.001026921,0.0001081021,0.0001616176,0.0001270155,0.0001911675],"domain_scores_gemma":[0.9979507,0.0006629041,0.0005469395,0.0001678773,0.0001821711,0.0004894376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9680513,0.007264279,0.001255166,0.0005733265,0.00147012,0.00004752817,0.00007725834,0.0003475926,0.004468559,0.00007549529,0.0007212989,0.01564814],"study_design_scores_gemma":[0.8587872,0.1346233,0.003989555,0.00003354905,0.0008675042,0.0000485798,0.00002271951,0.0002785252,0.0006480208,0.00007682342,0.0006055093,0.00001877898],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988937,0.00374272,0.0006772228,0.0004747211,0.0001532075,0.003229215,0.001294003,0.000105139,0.001386633],"genre_scores_gemma":[0.989004,0.002181972,0.00121405,0.0008182086,0.0002769674,0.003203688,0.001683825,0.00002685422,0.001590551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004685741,"threshold_uncertainty_score":0.02478087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0534512051383418,"score_gpt":0.3988051340151671,"score_spread":0.3453539288768253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}