{"id":"W2619120545","doi":"10.1128/jvi.00627-17","title":"The SAT Protein of Porcine Parvovirus Accelerates Viral Spreading through Induction of Irreversible Endoplasmic Reticulum Stress","year":2017,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"National Research, Development and Innovation Office; Hungarian Scientific Research Fund","keywords":"Unfolded protein response; Endoplasmic reticulum; Biology; CHOP; Thapsigargin; Parvovirus; XBP1; Cell biology; Virology; Molecular biology; Virus; RNA splicing; Genetics; RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001213193,0.000413415,0.0001929242,0.0001773728,0.000100975,0.0002317485,0.0001545229,0.000256668,0.0009226258],"category_scores_gemma":[0.0001321141,0.000141572,0.0003489931,0.0001290973,0.0001820004,0.0002072676,0.0002416801,0.0005555591,0.0003243307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001652538,"about_ca_system_score_gemma":0.00009004705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002217343,"about_ca_topic_score_gemma":0.0002500661,"domain_scores_codex":[0.9998358,0.00003297831,0.00001991754,0.00002552165,0.00005398618,0.00003169425],"domain_scores_gemma":[0.9998481,0.00003908041,0.00003869704,0.00002281859,0.0000203949,0.00003081503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002433974,0.000004776854,0.00006569819,0.00001342134,0.000001494369,0.00002714974,0.000002839482,0.00001085347,0.9996651,0.00001527624,0.000004955451,0.0001640396],"study_design_scores_gemma":[0.000006204092,0.0002759739,0.006085014,0.000003428611,0.000008785174,0.0002641834,0.00001965127,0.0006454531,0.9920719,0.00002915245,0.0005875919,0.000002821399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947325,0.0009590184,0.003163,0.00005442061,0.00003457882,0.00002140381,0.0002276904,0.00004417602,0.0007632061],"genre_scores_gemma":[0.9957665,0.0004163208,0.001735026,0.00003920373,0.0000137149,0.00001617877,0.0005812288,0.00001927441,0.001412458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009226258,"threshold_uncertainty_score":0.003086448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01347866169535328,"score_gpt":0.2769961970333282,"score_spread":0.2635175353379749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}