{"id":"W2619122711","doi":"10.1093/ndt/gfx113.mo002","title":"MO002APABETALONE (RVX-208) IMPACTS KEY BIOMARKERS AND PATHWAYS ASSOCIATED WITH CHRONIC KIDNEY DISEASE IN PATIENTS WITH SEVERE RENAL IMPAIRMENT","year":2017,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Blood Pressure and Hypertension Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Resverlogix (Canada)","funders":"","keywords":"Medicine; Kidney disease; Disease; Internal medicine; Kidney; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001883591,0.00020249,0.000275272,0.0001495774,0.0001218304,0.0002688884,0.0001010903,0.0001243062,0.001466365],"category_scores_gemma":[0.0002831627,0.00006590705,0.0001879359,0.000128426,0.000109925,0.0001251083,0.0001342796,0.000235808,0.0001408572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001862384,"about_ca_system_score_gemma":0.0003126584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005586745,"about_ca_topic_score_gemma":0.0009942391,"domain_scores_codex":[0.999931,0.00001649864,0.000004176941,0.00001695141,0.00001735064,0.000014047],"domain_scores_gemma":[0.9999038,0.00002145521,0.00003572461,0.000004743711,0.00001096952,0.00002322681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.03163676,0.001772529,0.2238018,0.0005802393,0.000443875,0.000355906,0.0001423967,0.001235365,0.5932654,0.00008986994,0.001001195,0.1456748],"study_design_scores_gemma":[0.001224699,0.01858196,0.9132832,0.00003801311,0.0003290957,0.001145268,0.000107657,0.002854659,0.0592192,0.0001903567,0.003007648,0.0000182535],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982623,0.001069143,0.0001428825,0.00004692264,0.000005763363,0.00001730183,0.0001553544,0.00001506285,0.0002854073],"genre_scores_gemma":[0.9986395,0.0004029759,0.0003777879,0.00004397973,0.000007942656,0.00002087982,0.0001689891,0.00000281337,0.0003350621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001466365,"threshold_uncertainty_score":0.004905462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009786461176721814,"score_gpt":0.2196088475219059,"score_spread":0.2098223863451841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}