{"id":"W2619298813","doi":"10.1177/0271678x17710182","title":"Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans","year":2017,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":199,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Medical Research Council; National Institute for Health and Care Research","keywords":"Translocator protein; Microglia; Inflammation; Cell biology; Macrophage; Chemistry; Gene expression; Biology; In vitro; Molecular biology; Immunology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005113425,0.0002598361,0.0005427073,0.000346149,0.0003044072,0.0002002308,0.0005332226,0.0001130927,0.00005683649],"category_scores_gemma":[0.0006095259,0.0002224876,0.0001407193,0.00009660425,0.000142262,0.001473442,0.0001035458,0.0003932197,0.000003318808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001708621,"about_ca_system_score_gemma":0.0001460804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001022903,"about_ca_topic_score_gemma":0.000004418708,"domain_scores_codex":[0.9973382,0.000387179,0.0009542185,0.0003522242,0.0007134069,0.0002547129],"domain_scores_gemma":[0.9978654,0.00007353334,0.001336248,0.0004091781,0.0001508276,0.0001648631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003164819,0.0002523012,0.0003385051,0.0001077529,0.000009210774,0.0000640478,0.0001804728,0.00004295454,0.9967893,0.0004437837,0.00002717416,0.001427955],"study_design_scores_gemma":[0.003230711,0.0001143084,0.02278101,0.0001990923,0.00005104654,0.00007615751,0.00001763703,0.0001373696,0.9727336,0.0003428863,0.0001336284,0.0001825818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983771,0.0001408608,0.0002478774,0.0002580668,0.0003168104,0.00053399,0.00002696454,0.00001985317,0.00007848617],"genre_scores_gemma":[0.9967317,0.0001537643,0.002304672,0.0002520073,0.0002767132,0.00001637605,0.000001492344,0.00003523254,0.0002280286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02405578,"threshold_uncertainty_score":0.9072782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02781055751886912,"score_gpt":0.2568707182839048,"score_spread":0.2290601607650357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}