{"id":"W2619352876","doi":"10.1002/anie.201702859","title":"Sol–Gel‐Derived Biohybrid Materials Incorporating Long‐Chain DNA Aptamers","year":2017,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aptamer; Nanotechnology; Molecular recognition; DNA; Biosensor; Small molecule; Materials science; Mesoporous material; Mesoporous silica; Nanometre; Combinatorial chemistry; Molecule; Chemistry; Biology; Biochemistry; Molecular biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002099465,0.0004078498,0.0002067122,0.0003186077,0.0001719968,0.0004168717,0.0002252316,0.0004642456,0.0009565363],"category_scores_gemma":[0.0001536591,0.0002887429,0.000243518,0.0001400949,0.0003010563,0.0003084336,0.0002316023,0.0004109527,0.0005922745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004311428,"about_ca_system_score_gemma":0.0001797806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002472369,"about_ca_topic_score_gemma":0.0007617148,"domain_scores_codex":[0.9998729,0.00001742829,0.000009193781,0.00003488014,0.00004278664,0.0000227379],"domain_scores_gemma":[0.9998682,0.0000504135,0.00002679717,0.00001288384,0.00001878316,0.00002289787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009989505,0.000006884845,0.00001668641,0.00001584572,0.000003157925,0.00001139682,0.000006207127,0.00004899336,0.9992875,0.00006433954,0.00002002255,0.0005089481],"study_design_scores_gemma":[0.000005780805,0.00004541781,0.0003091697,0.000001403654,0.00001031127,0.00006292801,0.000006284959,0.0004481175,0.9971611,0.00003555331,0.001909042,0.000004757002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.953176,0.002516874,0.03745708,0.0003691688,0.0001240504,0.0001339397,0.0004887737,0.0009166091,0.004817438],"genre_scores_gemma":[0.9652473,0.0008929797,0.02739705,0.0002227426,0.00004481129,0.0001380953,0.0005749243,0.0001122251,0.00536992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009565363,"threshold_uncertainty_score":0.003199935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01436031717731549,"score_gpt":0.2848372432724026,"score_spread":0.2704769260950871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}