{"id":"W2619562612","doi":"10.1016/s2213-2600(17)30190-x","title":"Benralizumab for patients with mild to moderate, persistent asthma (BISE): a randomised, double-blind, placebo-controlled, phase 3 trial","year":2017,"lang":"en","type":"article","venue":"The Lancet Respiratory Medicine","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Vancouver General Hospital; University of British Columbia","funders":"AstraZeneca","keywords":"Medicine; Benralizumab; Asthma; Placebo; Internal medicine; Dry-powder inhaler; Eosinophil; Inhaler; Mepolizumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002365853,0.001778418,0.004798028,0.0004541661,0.0006394497,0.001471427,0.001157573,0.003100678,0.008113668],"category_scores_gemma":[0.002221606,0.0008508656,0.003034562,0.0003944543,0.001483392,0.0012735,0.0005970778,0.003741236,0.001505828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007523452,"about_ca_system_score_gemma":0.001081043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001526025,"about_ca_topic_score_gemma":0.00322932,"domain_scores_codex":[0.9991892,0.0003848194,0.00005357299,0.0001479592,0.00007041344,0.0001539849],"domain_scores_gemma":[0.9990915,0.0003114828,0.0001761922,0.00006895389,0.00006456859,0.000287414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9882194,0.001621946,0.0002748964,0.001052427,0.0009264326,0.00002903949,0.000040864,0.00008533122,0.001387582,0.00007393264,0.000698599,0.005589427],"study_design_scores_gemma":[0.9890683,0.009558889,0.0005880382,0.00002844628,0.0002428725,0.00001411792,0.00001163911,0.0000577758,0.00006564034,0.00005686916,0.0003008778,0.00000641334],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9528121,0.02842274,0.001267844,0.002843471,0.002459101,0.005406019,0.002460015,0.0003129102,0.004015913],"genre_scores_gemma":[0.9728392,0.008709324,0.002143195,0.00356048,0.0009839907,0.00481234,0.001475384,0.00005111397,0.005424927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008113668,"threshold_uncertainty_score":0.02714294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08581923633290346,"score_gpt":0.3646516423486015,"score_spread":0.278832406015698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}