{"id":"W2619695335","doi":"10.1155/2017/2432904","title":"MCL Plays an Anti-Inflammatory Role in<i>Mycobacterium tuberculosis</i>-Induced Immune Response by Inhibiting NF-<i>κ</i>B and NLRP3 Inflammasome Activation","year":2017,"lang":"en","type":"article","venue":"Mediators of Inflammation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Shanghai Municipal Education Commission; National Natural Science Foundation of China","keywords":"Inflammasome; Immune system; Inflammatory response; Mycobacterium tuberculosis; Inflammation; NF-κB; Immunology; Tuberculosis; NFKB1; Microbiology; Medicine; Chemistry; Biology; Biochemistry; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001244833,0.0002873438,0.0002503667,0.0002563645,0.0001689085,0.0002656291,0.0001607926,0.0003192614,0.001822989],"category_scores_gemma":[0.00009613184,0.00008838355,0.0003086336,0.0001255176,0.0002421368,0.0002963657,0.000219726,0.0004793893,0.0003821391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001715609,"about_ca_system_score_gemma":0.0001875044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002123951,"about_ca_topic_score_gemma":0.0004074319,"domain_scores_codex":[0.9999335,0.00001441098,0.000007984584,0.000009773424,0.00001299235,0.00002129789],"domain_scores_gemma":[0.9999322,0.000008631604,0.00002695262,0.000003719966,0.000009669714,0.00001891565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004546443,0.00007044372,0.0003697124,0.0003228972,0.00001667341,0.0001308855,0.00001851335,0.0000805075,0.993758,0.0001421532,0.0001690336,0.00446655],"study_design_scores_gemma":[0.0001341899,0.002005447,0.007007446,0.00005924493,0.00007493255,0.0007525441,0.00007521972,0.0005507627,0.9746047,0.0002140858,0.01450583,0.00001555964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9333241,0.05333423,0.005834905,0.001322334,0.0001700076,0.00008762383,0.0006524652,0.000307453,0.00496683],"genre_scores_gemma":[0.9853973,0.00919271,0.002013898,0.0005428229,0.00005869172,0.00004404061,0.0004917053,0.00001456947,0.002244255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001822989,"threshold_uncertainty_score":0.006098449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004524093989513979,"score_gpt":0.2240307338924216,"score_spread":0.2195066399029076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}