{"id":"W2619770533","doi":"10.4049/jimmunol.1700141","title":"T Follicular Helper Cell–Derived IL-4 Is Required for IgE Production during Intestinal Helminth Infection","year":2017,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"RIKEN; Canadian Institutes of Health Research","keywords":"Germinal center; Immunoglobulin E; Immunology; Immune system; Immunoglobulin class switching; Biology; Plasma cell; Mesenteric lymph nodes; Lymph node; Cytokine; Interleukin 4; B cell; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000696593,0.0001878385,0.0003220769,0.0001726996,0.00122195,0.0000419698,0.0003912262,0.0002157733,0.000365004],"category_scores_gemma":[0.0006043071,0.0001329164,0.00023276,0.0000496969,0.000329486,0.0004674956,0.0001030719,0.0005787525,0.0001740332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001118323,"about_ca_system_score_gemma":0.00006294085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000118151,"about_ca_topic_score_gemma":0.00001064713,"domain_scores_codex":[0.9986642,0.0002664504,0.0005563498,0.0001638444,0.00004469422,0.0003044376],"domain_scores_gemma":[0.9976454,0.0001013502,0.00122918,0.0005313604,0.0004787126,0.00001398161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002399387,0.0001208999,0.0004398276,0.00002065494,0.0003288938,0.00000194152,0.0007773557,0.00001326425,0.9898053,0.00002526776,0.004076517,0.00199067],"study_design_scores_gemma":[0.001922565,0.0008320261,0.02292632,0.0000774,0.0001662862,0.001992718,0.0004687076,0.000004658087,0.9342948,0.000106931,0.03706791,0.0001396358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834123,0.001669555,0.001412923,0.002200638,0.0106824,0.0002788044,0.000001773081,0.00002628308,0.0003153389],"genre_scores_gemma":[0.989808,0.0008779371,0.00007189647,0.0001049634,0.000254931,0.0000130556,0.000008355982,0.00002251323,0.008838342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05551048,"threshold_uncertainty_score":0.9398373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01860145919344539,"score_gpt":0.2522715222025295,"score_spread":0.2336700630090841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}