{"id":"W2619988375","doi":"10.1093/molehr/gax029","title":"Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation","year":2017,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; McGill University; William Osler Health System; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Methylation; Folic acid; Folic acid supplementation; Genomic imprinting; DNA methylation; Endocrinology; Genetics; Imprinting (psychology); Gene; Internal medicine; Pregnancy; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003542916,0.0001578639,0.0001554707,0.00009345945,0.0002369578,0.00007341768,0.0001073666,0.00005813897,0.0000121611],"category_scores_gemma":[0.000278544,0.000145973,0.00007546728,0.00003098514,0.00006954111,0.00001211293,0.00015791,0.00005182185,0.000001008403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001983032,"about_ca_system_score_gemma":0.00002066094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002064675,"about_ca_topic_score_gemma":0.00001810689,"domain_scores_codex":[0.9986709,0.00006094414,0.0002722135,0.0006917712,0.0001558113,0.0001483929],"domain_scores_gemma":[0.9988716,0.000002437456,0.0002339864,0.0007077013,0.000124907,0.00005938314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002916213,0.00004179126,0.09828176,0.000008872502,0.00006123453,4.502261e-7,0.0001389627,0.0002134072,0.8959473,0.00006032367,0.00002193204,0.005194753],"study_design_scores_gemma":[0.0002355001,0.0005836794,0.477142,0.000005764135,0.00001368464,0.00001390231,0.00001528695,0.000014611,0.5217672,0.0001087839,0.00001647418,0.00008312092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954171,0.0001739125,0.003659206,0.0002415694,0.0001276343,0.000307045,0.00001041548,0.000007052619,0.00005607571],"genre_scores_gemma":[0.9976169,0.00002788728,0.001955853,0.00002394855,0.0001472926,0.00002266618,0.00007422064,0.00001874376,0.0001124538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3788603,"threshold_uncertainty_score":0.5952608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01666211461636326,"score_gpt":0.3195948542729148,"score_spread":0.3029327396565516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}