{"id":"W2620106993","doi":"10.1208/s12249-017-0802-5","title":"Development and Evaluation of a Family of Human Face and Upper Airway Models for the Laboratory Testing of Orally Inhaled Products","year":2017,"lang":"en","type":"article","venue":"AAPS PharmSciTech","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Trudell Medical International (Canada)","funders":"","keywords":"Mouthpiece; Airway; Medicine; Salbutamol; Inhaler; Metered-dose inhaler; Aerosolization; Terbutaline; Anesthesia; Biomedical engineering; Asthma; Inhalation; Dentistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00133037,0.00008617978,0.0002039959,0.00007624422,0.0001812861,0.00001008503,0.00008200834,0.00004762368,0.00000359521],"category_scores_gemma":[0.0003904956,0.00005891729,0.00001766664,0.00008356347,0.0001702874,0.0001242477,0.00005290973,0.00006253358,2.19032e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001703818,"about_ca_system_score_gemma":0.0002864312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009083024,"about_ca_topic_score_gemma":0.000002403607,"domain_scores_codex":[0.9990925,0.00003311457,0.0003040409,0.0001593755,0.0003229845,0.00008804039],"domain_scores_gemma":[0.9981027,0.00006747387,0.000327506,0.0002585597,0.001213043,0.000030717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008007006,0.00009658986,0.003937403,0.0005771315,0.00008519446,8.723451e-7,0.002461194,0.0001233452,0.9508374,0.0001804594,0.0001209891,0.0414994],"study_design_scores_gemma":[0.003667794,0.0001861472,0.02812184,0.000346329,0.000274081,0.000004994634,0.0007118137,0.01837697,0.9476277,0.0001073277,0.0004483367,0.0001267307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974952,0.000841715,0.0001590933,0.0001515657,0.00004066897,0.0008753779,0.00001118487,0.000008284981,0.0004169546],"genre_scores_gemma":[0.9963008,0.00001498273,0.003463773,0.00006308469,0.00002912073,0.00003276041,0.000003625599,0.00001048295,0.0000813301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04137267,"threshold_uncertainty_score":0.2402578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1505093410852556,"score_gpt":0.368808516299671,"score_spread":0.2182991752144154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}