{"id":"W2620659072","doi":"10.1016/j.nucmedbio.2017.05.011","title":"Evaluation of a novel radiotracer for positron emission tomography imaging of reactive oxygen species in the central nervous system","year":2017,"lang":"en","type":"article","venue":"Nuclear Medicine and Biology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Ex vivo; Radiosynthesis; In vivo; Chemistry; Biodistribution; Positron emission tomography; Preclinical imaging; Reactive oxygen species; Nuclear medicine; Biochemistry; Medicine; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001284687,0.00007562005,0.0002897319,0.0001050167,0.00006468441,0.000002787462,0.00008427977,0.00005934825,0.000007825689],"category_scores_gemma":[0.0004321457,0.00004086988,0.00005027146,0.00004911329,0.0002093384,0.00003029311,0.00001645005,0.0000781139,9.140223e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002210203,"about_ca_system_score_gemma":0.00002413511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003777707,"about_ca_topic_score_gemma":0.000005812061,"domain_scores_codex":[0.9993095,0.00008551633,0.0001957338,0.0001285949,0.0001453202,0.0001353354],"domain_scores_gemma":[0.9992933,0.0001410146,0.000185542,0.0002046661,0.0001423146,0.00003315743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007848155,0.0001488728,0.05774662,0.0003592123,0.0001089928,0.000003863971,0.003502812,9.849178e-7,0.8948792,0.001026681,0.0008665682,0.04057139],"study_design_scores_gemma":[0.009357391,0.001282322,0.9676056,0.000896193,0.0007982702,0.0001254934,0.006450969,0.00722719,0.003677621,0.0001635487,0.002324609,0.00009077678],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993574,0.000912743,0.00009732429,0.002427546,0.0001221069,0.0005494863,0.000008428558,0.000006040583,0.002302352],"genre_scores_gemma":[0.9992709,0.00005603268,0.0002617147,0.0001554424,0.0002225164,0.000006674013,0.00001041626,0.000007041407,0.000009245231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.909859,"threshold_uncertainty_score":0.1666625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07599949662452643,"score_gpt":0.3500845258082569,"score_spread":0.2740850291837305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}