{"id":"W2620885951","doi":"10.1139/cjc-2017-0335","title":"Genetically modified human type II collagen for N- and C-terminal covalent tagging","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Collagen: Extraction and Characterization","field":"Materials Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"HT1080; Chemistry; Biochemistry; Procollagen peptidase; Connective tissue; Cysteine; Type I collagen; Transfection; Protein engineering; Secretion; Enzyme; Molecular biology; Cell; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000178865,0.00006971016,0.0001184001,0.00002503503,0.0007034982,0.0002451594,0.0002071978,0.00006004061,0.0006484847],"category_scores_gemma":[0.0001288881,0.00007107666,0.00003191993,0.00001521401,0.00009189876,0.0001160172,0.00001618039,0.00004246723,0.000001746802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006543967,"about_ca_system_score_gemma":0.0004901317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006573648,"about_ca_topic_score_gemma":0.0002743569,"domain_scores_codex":[0.9994564,0.000006510812,0.0002007178,0.00009501391,0.00008390888,0.0001574277],"domain_scores_gemma":[0.9990216,0.000009865958,0.0002751233,0.0001497166,0.0001995717,0.0003441517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002040275,0.000005151126,0.0001781207,0.00003698434,0.000005001334,0.0000395013,0.0001106111,0.000005513556,0.9981162,0.00002601965,0.0008249295,0.000631574],"study_design_scores_gemma":[0.0009125558,0.0001184037,0.01041204,0.0001175942,0.00004631956,0.0005441813,0.0001032782,0.0001616804,0.9485745,0.0002320572,0.03854972,0.0002275985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970246,0.00006786557,0.0001592149,0.0005730466,0.0003032813,0.00005493974,0.00002442773,0.000003036397,0.001789612],"genre_scores_gemma":[0.9978771,0.000008852279,0.0002685426,0.00008739733,0.0003042603,0.000001547913,0.000004124424,0.000008284193,0.001439913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04954163,"threshold_uncertainty_score":0.7100453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02846191025482151,"score_gpt":0.2755835056928141,"score_spread":0.2471215954379926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}