{"id":"W2621014178","doi":"10.1523/jneurosci.3250-16.2017","title":"Reduced Slc6a15 in Nucleus Accumbens D2-Neurons Underlies Stress Susceptibility","year":2017,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression","keywords":"Nucleus accumbens; Social defeat; Medium spiny neuron; Striatum; Neuroscience; Dopamine receptor D2; Dopamine; Choline acetyltransferase; Neuron; Biology; Chemistry; Cholinergic","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007458787,0.0002911201,0.0002193343,0.0003019532,0.0001952866,0.0002280607,0.0001296899,0.0003162379,0.001549799],"category_scores_gemma":[0.00010575,0.000138744,0.0002624727,0.0001097517,0.0003027182,0.0001043731,0.0002440631,0.0004241792,0.0001592222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000300586,"about_ca_system_score_gemma":0.0001581353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001946231,"about_ca_topic_score_gemma":0.003740186,"domain_scores_codex":[0.9999032,0.000008495974,0.00001079663,0.0000358937,0.00002207289,0.00001944076],"domain_scores_gemma":[0.9998733,0.000006492999,0.0000500567,0.000009800284,0.00001252105,0.00004787397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002788764,0.0000328094,0.007835504,0.00003551007,0.00002701871,0.000238208,0.00004754035,0.00003998648,0.9899884,0.00006873842,0.00009182117,0.001315616],"study_design_scores_gemma":[0.00005017698,0.0006556753,0.6618135,0.00003700803,0.00009344143,0.003649383,0.0002919129,0.00132494,0.3294038,0.000309813,0.002345157,0.00002512403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978491,0.0004022233,0.0006911802,0.00008017176,0.0000120028,0.00001614274,0.0004050514,0.00003282552,0.0005112976],"genre_scores_gemma":[0.9986172,0.0001973757,0.0003408214,0.00005662136,0.000003656187,0.00001382569,0.0002378625,0.000007692095,0.0005250208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001946231,"threshold_uncertainty_score":0.00518465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0401776578929494,"score_gpt":0.3136789664284038,"score_spread":0.2735013085354544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}