{"id":"W2621067345","doi":"10.1016/j.neuro.2017.05.011","title":"Retinoic acid prevents synaptic deficiencies induced by alcohol exposure during gastrulation in zebrafish embryos","year":2017,"lang":"en","type":"article","venue":"NeuroToxicology","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gastrulation; Zebrafish; Mauthner cell; Epiboly; Cell biology; Biology; Embryo; Retinoic acid; Excitatory postsynaptic potential; Ethanol; Internal medicine; Chemistry; Endocrinology; Embryogenesis; Anatomy; Andrology; Biochemistry; Cell culture; Inhibitory postsynaptic potential; Fish <Actinopterygii>; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000176053,0.0004643148,0.0003944812,0.0004699969,0.0002425823,0.0002808055,0.0003949843,0.0004122639,0.002008421],"category_scores_gemma":[0.0002284411,0.0003249587,0.0003113226,0.0001176866,0.0005403553,0.0003738909,0.0004114115,0.0009471542,0.0003330615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006419366,"about_ca_system_score_gemma":0.0006260292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004779312,"about_ca_topic_score_gemma":0.01150355,"domain_scores_codex":[0.9998143,0.00002426654,0.00002341658,0.00003632234,0.00004040986,0.00006130597],"domain_scores_gemma":[0.9997298,0.00003366748,0.0001000825,0.00003012326,0.00003325468,0.00007304503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002316819,0.000009671011,0.0001684,0.00001761646,0.000004421339,0.00007426667,0.00002877192,0.00002184469,0.9988633,0.00006285073,0.00001837232,0.0004987621],"study_design_scores_gemma":[0.00003024512,0.0002647658,0.005944779,0.00001070068,0.00003209735,0.0001151892,0.0001092144,0.0002496005,0.9921601,0.00005762753,0.001017713,0.000007890949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965276,0.001011915,0.0009046515,0.0001647732,0.00003418351,0.00001768092,0.000267616,0.0000773575,0.0009941463],"genre_scores_gemma":[0.9922299,0.0008192398,0.0008923184,0.00006157799,0.000008599878,0.00003394205,0.0002235022,0.00004292523,0.005687999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004779312,"threshold_uncertainty_score":0.009503007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02349870102124455,"score_gpt":0.3084535448399847,"score_spread":0.2849548438187401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}