{"id":"W2621081192","doi":"10.1158/1078-0432.ccr-17-0702","title":"Pediatric Cancer Predisposition and Surveillance: An Overview, and a Tribute to Alfred G. Knudson Jr","year":2017,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Childhood Cancer Survivors' Quality of Life","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Human Genome Research Institute; National Institutes of Health; General Motors Foundation","keywords":"Cancer; Medicine; Genetic predisposition; Pediatric cancer; Genetic testing; Family medicine; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01188572,0.0006851123,0.004351054,0.0005630795,0.0005246531,0.0003212751,0.0007392795,0.001031728,0.0003112954],"category_scores_gemma":[0.003650702,0.0005762904,0.0005312395,0.0008026921,0.0006149889,0.0002403148,0.0008380779,0.002895928,0.00006397848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005658023,"about_ca_system_score_gemma":0.003619646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005886515,"about_ca_topic_score_gemma":0.006208296,"domain_scores_codex":[0.9899712,0.002914286,0.002036167,0.002098989,0.001814301,0.00116506],"domain_scores_gemma":[0.9921474,0.002460433,0.0006980291,0.001912386,0.0008399078,0.001941816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005258225,0.0002581431,0.01381005,0.03187561,0.0003080555,0.00005569731,0.0001799729,1.343575e-7,2.719839e-7,0.00001681293,0.03747092,0.9154985],"study_design_scores_gemma":[0.001930517,0.001390098,0.0413609,0.01197954,0.000685992,0.00003011872,0.00002540486,0.000008717868,3.107856e-7,0.00006998277,0.9419382,0.0005801965],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005227394,0.9823283,0.000004015963,0.00547201,0.00103397,0.003930256,0.001771128,0.00008754032,0.0001453731],"genre_scores_gemma":[0.0002635187,0.9872973,0.00008640323,0.0005756221,0.00816958,0.001431503,0.0003420867,0.0001607984,0.001673199],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9149183,"threshold_uncertainty_score":0.9996688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6250210048115101,"score_gpt":0.6573310754797627,"score_spread":0.03231007066825253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}