{"id":"W2621164287","doi":"10.1016/j.molcel.2017.05.029","title":"DNA Replication Is Required for Circadian Clock Function by Regulating Rhythmic Nucleosome Composition","year":2017,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Key Research and Development Program of China; U.S. Department of the Interior; Fonds de Recherche du Québec - Santé; National Institutes of Health; Cancer Prevention and Research Institute of Texas; Welch Foundation","keywords":"Biology; Circadian clock; DNA replication; Eukaryotic DNA replication; Control of chromosome duplication; Origin recognition complex; Circadian rhythm; Genetics; Cell biology; Pre-replication complex; Nucleosome; Licensing factor; DNA re-replication; Oscillating gene; Histone; Bacterial circadian rhythms; DNA; Gene; Neuroscience","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002000152,0.0002647288,0.0002801939,0.000265092,0.0005059516,0.0008615682,0.000470302,0.0004367672,0.00187839],"category_scores_gemma":[0.0005718414,0.0004178223,0.0002867633,0.0001724763,0.0003844973,0.0006524638,0.0005537543,0.0005077936,0.0008561343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007503226,"about_ca_system_score_gemma":0.0004435932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002080097,"about_ca_topic_score_gemma":0.005010897,"domain_scores_codex":[0.9998143,0.00001384051,0.00001206815,0.00007287328,0.00004166307,0.00004527533],"domain_scores_gemma":[0.9996668,0.00003699871,0.00009416271,0.00005556569,0.00005920124,0.00008726027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001665584,0.000009844575,0.001003828,0.0000232285,0.000007347513,0.0000483693,0.00002819315,0.00004742515,0.9955641,0.0004322959,0.0001319479,0.002536916],"study_design_scores_gemma":[0.00005024678,0.0001680901,0.06202342,0.0000206355,0.00002323202,0.0002949274,0.0001338717,0.002249017,0.9274936,0.001183224,0.006334207,0.00002562175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9651893,0.00981801,0.01711777,0.0007139316,0.0005311397,0.0000405795,0.0006926023,0.0007227599,0.005173901],"genre_scores_gemma":[0.9914601,0.0008051526,0.003149298,0.00009512307,0.00004806344,0.00001576808,0.0006192944,0.0001135325,0.003693633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002080097,"threshold_uncertainty_score":0.00628382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02157431230832398,"score_gpt":0.2564140812789906,"score_spread":0.2348397689706666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}