{"id":"W2621232571","doi":"10.1016/j.ceb.2017.05.007","title":"Translational control and the cancer cell response to stress","year":2017,"lang":"en","type":"review","venue":"Current Opinion in Cell Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Carcinogenesis; Chromatin; Translation (biology); Cancer cell; Translational regulation; Cancer; Cell biology; Polysome; RNA splicing; Phenotype; Alternative splicing; Messenger RNA; Translational efficiency; Transcription (linguistics); Ribosome; Computational biology; Genetics; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008332489,0.0003063375,0.0007314014,0.00005948394,0.000108955,0.0000304519,0.0005222166,0.0004088844,0.00003684722],"category_scores_gemma":[0.00008836249,0.0001985959,0.0002137088,0.00003544777,0.0001569662,0.000002222105,0.0001128953,0.0001856086,0.00001219034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001706082,"about_ca_system_score_gemma":0.0002416156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000310398,"about_ca_topic_score_gemma":0.0000166177,"domain_scores_codex":[0.9976773,0.001020182,0.0004075333,0.0005667179,0.00006736287,0.0002609036],"domain_scores_gemma":[0.998869,0.0002354122,0.0002767428,0.0005069273,0.00003491479,0.00007702635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007534498,0.00005175819,0.0000340696,0.002629997,0.00003995277,2.157e-7,0.00004120996,0.000003294457,0.001830738,0.0001434695,0.000491121,0.9939807],"study_design_scores_gemma":[0.00116036,0.00009336278,0.000009578381,0.00123772,0.00004924398,0.00000174268,0.000004449196,0.000003011864,0.0003681583,0.00005900891,0.9967712,0.0002421226],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005021733,0.9950171,0.0004327901,0.0001815868,0.002447203,0.001151726,0.0005556278,0.000003977384,0.0001597713],"genre_scores_gemma":[0.0008770548,0.9973121,0.000043233,0.0000272838,0.0006199577,0.0007030535,0.0002598552,0.00002492435,0.0001325196],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9962801,"threshold_uncertainty_score":0.8098506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07962882614320568,"score_gpt":0.3931150898992259,"score_spread":0.3134862637560202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}