{"id":"W2621262249","doi":"10.1186/s12863-017-0509-3","title":"In vivo screening reveals interactions between Drosophila Manf and genes involved in the mitochondria and the ubiquinone synthesis pathway","year":2017,"lang":"en","type":"article","venue":"BMC Genetics","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Parkinsonfonden; Helsingin Yliopisto; Ella ja Georg Ehrnroothin Säätiö; Suomen Parkinson-säätiö; Institute of Genetics; Academy of Finland; Eesti Teadusagentuur; Alfred Kordelinin Säätiö","keywords":"Biology; Neurotrophic factors; RNA interference; Drosophila melanogaster; Gene; Cell biology; Endoplasmic reticulum; Function (biology); Genetics; Drosophila (subgenus); Mitochondrion; Receptor; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001770192,0.0003956849,0.0001852254,0.0003731421,0.0002123143,0.0002364598,0.0003578079,0.0004260103,0.002042825],"category_scores_gemma":[0.0001280615,0.0001840258,0.0002849341,0.0001405592,0.0001811113,0.0001161389,0.0002449347,0.0004552328,0.0006646801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005372828,"about_ca_system_score_gemma":0.0001938439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001022779,"about_ca_topic_score_gemma":0.001740122,"domain_scores_codex":[0.9998203,0.00002220097,0.00001207453,0.00005687629,0.00005545203,0.00003322611],"domain_scores_gemma":[0.9997932,0.00006624084,0.00006277254,0.00001513862,0.00001351997,0.00004908117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002872408,0.00001318219,0.0003311065,0.00001488609,0.000004193001,0.00006376535,0.000006330488,0.00002526965,0.9989787,0.00005373376,0.00002330677,0.0004568306],"study_design_scores_gemma":[0.00001564255,0.0001239958,0.01090682,0.000005922514,0.00002518523,0.0006952747,0.00003564295,0.001444416,0.9835501,0.00003890321,0.003152708,0.000005463267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888311,0.001446982,0.006569985,0.0001285097,0.00002389833,0.00004524983,0.0008154165,0.00009164722,0.00204723],"genre_scores_gemma":[0.9853581,0.0004741379,0.007957838,0.0001096591,0.000008413946,0.00004927003,0.00180439,0.00005991975,0.004178245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002042825,"threshold_uncertainty_score":0.006833971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02680098952950975,"score_gpt":0.2791405742265572,"score_spread":0.2523395846970474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}