{"id":"W2621324164","doi":"10.1016/j.abb.2017.05.017","title":"The type II isopentenyl Diphosphate:Dimethylallyl diphosphate isomerase (IDI-2): A model for acid/base chemistry in flavoenzyme catalysis","year":2017,"lang":"en","type":"review","venue":"Archives of Biochemistry and Biophysics","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institutes of Health; National Institute of General Medical Sciences; McGill University; Welch Foundation","keywords":"Chemistry; Flavin group; Isomerase; Cofactor; Isoprene; Isopentenyl pyrophosphate; Catalysis; Enzyme catalysis; Stereochemistry; Pyrophosphate; Biochemistry; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003746879,0.0008096957,0.0007256243,0.0009863572,0.0001966315,0.0007934296,0.0007670383,0.0008411987,0.001808764],"category_scores_gemma":[0.0002954378,0.000222351,0.0002465679,0.00140374,0.0005615103,0.001502671,0.00065809,0.001312006,0.001561313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006820188,"about_ca_system_score_gemma":0.0009306424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006128837,"about_ca_topic_score_gemma":0.001115721,"domain_scores_codex":[0.9999305,0.000008049587,0.000008901663,0.00001836713,0.00002381493,0.00001029905],"domain_scores_gemma":[0.9999126,0.00002921668,0.00001839053,0.000004099852,0.00002112506,0.00001462888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007533507,0.00004208599,0.0001257312,0.01068132,0.00005624794,0.0002577266,0.00004407526,0.000503912,0.006376795,0.01368673,0.03009621,0.9380539],"study_design_scores_gemma":[0.00001199698,0.00004825065,0.0001445844,0.0007264234,0.00004608827,0.0005292458,0.00002506419,0.00008686707,0.001188781,0.003344023,0.9938392,0.000009550062],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000220709,0.9969212,0.0005800397,0.0003574516,0.0004371256,0.000004343472,0.00002266369,0.00001234082,0.001444059],"genre_scores_gemma":[0.001755712,0.9960669,0.0005091403,0.0002389964,0.000251519,0.000006537721,0.00003904844,0.000002043962,0.001130168],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001808764,"threshold_uncertainty_score":0.006050885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03192632949108096,"score_gpt":0.2950097164455545,"score_spread":0.2630833869544735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}