{"id":"W2621372813","doi":"10.1371/journal.ppat.1006394","title":"Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein","year":2017,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Effector; Legionella pneumophila; ATPase; Protein subunit; Biology; Cell biology; Biochemistry; Biophysics; Bacteria; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001047213,0.0002446934,0.0002278801,0.0001022548,0.0002171296,0.0002962685,0.0004607941,0.0006315323,0.000820527],"category_scores_gemma":[0.000130689,0.0001732266,0.0003229928,0.00008379987,0.0003053711,0.0002619884,0.0002199353,0.0005159781,0.0006454459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004140253,"about_ca_system_score_gemma":0.0001752185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005115728,"about_ca_topic_score_gemma":0.0003341123,"domain_scores_codex":[0.999911,0.00000899043,0.000009253868,0.00002637273,0.00002550851,0.00001883075],"domain_scores_gemma":[0.9999274,0.00001148467,0.00001647838,0.000008078238,0.00001077584,0.00002589285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001097119,0.00004323742,0.0005342921,0.00004553657,0.000006584892,0.0002556055,0.00001154378,0.0002403549,0.9972336,0.0006338939,0.00006627073,0.0008193987],"study_design_scores_gemma":[0.00005664185,0.0002957635,0.0172387,0.00001353809,0.00001679913,0.001237228,0.00005499191,0.009082775,0.9682516,0.0005595746,0.003177635,0.00001454317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898288,0.001919956,0.005349343,0.0003166479,0.00008564847,0.00003144677,0.0001692226,0.0001090772,0.002189796],"genre_scores_gemma":[0.9963424,0.0005142706,0.001849947,0.00008719547,0.00001111258,0.00001456116,0.0001856494,0.00001349684,0.0009813515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000820527,"threshold_uncertainty_score":0.003004014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02007159207495355,"score_gpt":0.2825153972953394,"score_spread":0.2624438052203859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}