{"id":"W2621474688","doi":"10.1158/1557-3265.ovcasymp16-ntoc-093","title":"Abstract NTOC-093: SYNTHETIC LETHAL APPROACHES TO TARGET ARID1A DEFICIENT OVARIAN CANCERS","year":2017,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"ARID1A; Synthetic lethality; Cancer research; Ovarian cancer; Clear cell carcinoma; Clear cell; Serous fluid; Biology; Cancer; Endometrial cancer; Ovarian carcinoma; Medicine; DNA repair; Carcinoma; Mutation; Internal medicine; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001675952,0.0005026183,0.0004125308,0.0004503422,0.0001839906,0.0002988193,0.0004076384,0.0003028059,0.00305874],"category_scores_gemma":[0.0001043899,0.0001460665,0.0003396832,0.0002997,0.0001868901,0.0001538636,0.0002098739,0.0008329172,0.0005688095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004054756,"about_ca_system_score_gemma":0.0004488172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001083132,"about_ca_topic_score_gemma":0.002750239,"domain_scores_codex":[0.9999021,0.00001668554,0.00000833814,0.00001637981,0.00003227568,0.00002409676],"domain_scores_gemma":[0.9999375,0.00001014694,0.00001196097,0.000006285915,0.00001137526,0.00002282831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007847588,0.0005509121,0.0002725317,0.0001958623,0.00002864852,0.0001554516,0.00002065382,0.001297384,0.9834573,0.000443356,0.0009034052,0.01188976],"study_design_scores_gemma":[0.0007232807,0.009951822,0.004281056,0.00003351763,0.0001060987,0.0008925445,0.00005673894,0.003088574,0.9594675,0.0002081676,0.02115815,0.00003244256],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9697724,0.005450549,0.007328299,0.0004782841,0.0002292446,0.0006888828,0.006098582,0.0005466514,0.009407085],"genre_scores_gemma":[0.9699776,0.004543114,0.007603435,0.0002646012,0.00002736745,0.000388878,0.006111067,0.00006497121,0.01101897],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.00305874,"threshold_uncertainty_score":0.01023245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4763574319646575,"score_gpt":0.5026225866717711,"score_spread":0.02626515470711355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}