{"id":"W2621474688","doi":"10.1158/1557-3265.ovcasymp16-ntoc-093","title":"Abstract NTOC-093: SYNTHETIC LETHAL APPROACHES TO TARGET ARID1A DEFICIENT OVARIAN CANCERS","year":2017,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"ARID1A; Synthetic lethality; Cancer research; Ovarian cancer; Clear cell carcinoma; Clear cell; Serous fluid; Biology; Cancer; Endometrial cancer; Ovarian carcinoma; Medicine; DNA repair; Carcinoma; Mutation; Internal medicine; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002867772,0.0002053457,0.0003133492,0.00006259559,0.0006696603,0.0002205166,0.001114158,0.0003103621,0.0002464566],"category_scores_gemma":[0.001239917,0.0001838414,0.0002209435,0.00007522935,0.0005928352,0.000007762401,0.0005701,0.0006531022,0.000107545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001772443,"about_ca_system_score_gemma":0.001078157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002832392,"about_ca_topic_score_gemma":0.001082745,"domain_scores_codex":[0.9969711,0.0001852022,0.0004963489,0.0009612858,0.0006197102,0.000766351],"domain_scores_gemma":[0.9975226,0.0001056762,0.0001427538,0.001555137,0.0002253758,0.0004484825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006737477,0.001923714,0.06932031,0.0009334933,0.001195947,0.0002891372,0.001074454,0.03580329,0.1766472,0.002162112,0.1370232,0.5668897],"study_design_scores_gemma":[0.005935276,0.002760194,0.207755,0.0008961516,0.000108619,0.00004513017,0.0007952469,0.007824739,0.1171022,0.002917371,0.6513354,0.002524608],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757072,0.001702865,0.0006685528,0.003699206,0.0008224541,0.0005493723,0.00007773028,0.00002136086,0.01675132],"genre_scores_gemma":[0.9946496,0.0004281529,0.0009655506,0.0002661475,0.001451387,0.0002644632,0.00002076479,0.00004739971,0.001906469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5643651,"threshold_uncertainty_score":0.7496833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4763574319646575,"score_gpt":0.5026225866717711,"score_spread":0.02626515470711355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}