{"id":"W2621511700","doi":"10.1038/ncomms15743","title":"DNA vaccination protects mice against Zika virus-induced damage to the testes","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency; Canadian Science Centre for Human and Animal Health; Wilfrid Laurier University; University of Winnipeg; Université Laval; University of Manitoba; Public Health Agency of Canada","funders":"Defense Advanced Research Projects Agency; Centers for Disease Control and Prevention; Public Health Agency; INOVIO Pharmaceuticals; Université Laval; National Institutes of Health; Public Health Agency of Canada; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Zika virus; Microcephaly; Virology; Biology; Vaccination; DNA vaccination; Sexual transmission; Virus; DNA damage; Semen; Sperm; Immunology; Immunization; DNA; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0002707884,0.0001391921,0.0001784221,0.00006708939,0.001305013,0.0001700089,0.001732895,0.0001815855,0.0000281684],"category_scores_gemma":[0.001834609,0.00009907227,0.0001044782,0.000146876,0.00003831223,0.0001453167,0.0004571633,0.0008117074,0.00009535027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000615173,"about_ca_system_score_gemma":0.000119353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006934226,"about_ca_topic_score_gemma":0.00138148,"domain_scores_codex":[0.9990914,0.0001029799,0.000185151,0.0002073686,0.000222944,0.0001901549],"domain_scores_gemma":[0.9944586,0.0001743531,0.0001682563,0.004717037,0.0003417097,0.0001400568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005276102,0.002209953,0.01370438,0.0001770879,0.0005651258,0.00002561977,0.002315584,0.00001859012,0.5542307,0.04169036,0.07068006,0.3138548],"study_design_scores_gemma":[0.001349922,0.0001330926,0.7639925,0.0001428688,0.0001938681,0.000005211033,0.0002214264,0.001870052,0.006169341,0.0001752735,0.2255197,0.000226756],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.680771,0.005589429,0.00007409265,0.2619183,0.0003752894,0.004089931,0.0001028814,0.0002165454,0.04686258],"genre_scores_gemma":[0.9927028,0.0001672752,0.0006614363,0.005244639,0.0001990928,0.000368725,0.00007623436,0.00002332198,0.0005564158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7502881,"threshold_uncertainty_score":0.9999952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0277364185110711,"score_gpt":0.3434304069484256,"score_spread":0.3156939884373545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}