{"id":"W2622000415","doi":"10.1074/jbc.m117.780304","title":"Cell adhesion controlled by adhesion G protein–coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo–Dock","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Consejo Nacional de Ciencia y Tecnología","keywords":"CDC42; Lamellipodium; Cell biology; Guanine nucleotide exchange factor; Cell adhesion; Filopodia; GTPase; Rac GTP-Binding Proteins; Cell migration; Chemistry; L1; Biology; Adhesion; Signal transduction; RAC1; Actin; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009856759,0.0003291088,0.0001674002,0.0002116534,0.000209199,0.0002801332,0.0001872705,0.0002246744,0.001139104],"category_scores_gemma":[0.00007898982,0.0001371929,0.000296129,0.0001409946,0.0001787873,0.0001553449,0.0003596997,0.0003180723,0.0003934803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004928079,"about_ca_system_score_gemma":0.0001157779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004201286,"about_ca_topic_score_gemma":0.0006218766,"domain_scores_codex":[0.9998301,0.00003630996,0.00001012376,0.00003658399,0.00003481955,0.00005199342],"domain_scores_gemma":[0.9999647,0.000002505634,0.00001537088,0.000004456405,0.000002843252,0.00001006057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001156386,0.00001166509,0.0002908749,0.00002209899,0.000006718898,0.0001017115,0.00001000492,0.00008260427,0.9985182,0.0002022449,0.00006077059,0.0005776923],"study_design_scores_gemma":[0.00006050762,0.0002829356,0.0255057,0.00001102447,0.00004339322,0.001860063,0.00008823374,0.004475159,0.9590499,0.0001607965,0.008450809,0.00001143594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963726,0.0008255146,0.001399685,0.00007408627,0.00000960791,0.00001085174,0.0001943186,0.00002852918,0.001084923],"genre_scores_gemma":[0.9971653,0.0003591796,0.0008717154,0.00003456979,0.00000442026,0.00001374934,0.0004572598,0.000004267055,0.001089606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001139104,"threshold_uncertainty_score":0.003810704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03709837008212748,"score_gpt":0.3066525805895929,"score_spread":0.2695542105074654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}