{"id":"W2622034410","doi":"10.2196/resprot.7493","title":"Pain Improvement With Novel Combination Analgesic Regimens (PAIN-CARE): Randomized Controlled Trial Protocol","year":2017,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Queen's University","funders":"","keywords":"Medicine; Pregabalin; Postherpetic neuralgia; Adverse effect; Analgesic; Population; Neuropathic pain; Placebo; Randomized controlled trial; Combination therapy; Clinical trial; Anesthesia; Pharmacology; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01003938,0.006003829,0.0104597,0.001982534,0.002225336,0.0025516,0.003465885,0.005891172,0.06255989],"category_scores_gemma":[0.009568998,0.0024126,0.004222469,0.002209857,0.002993966,0.002657848,0.001606289,0.005538071,0.007673529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002693194,"about_ca_system_score_gemma":0.009736155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002000655,"about_ca_topic_score_gemma":0.004768574,"domain_scores_codex":[0.9932171,0.003583935,0.000683219,0.0008928285,0.0006006837,0.00102241],"domain_scores_gemma":[0.9949292,0.001295518,0.001406114,0.0004608523,0.0008839619,0.001024449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.968336,0.00898514,0.0002862465,0.006098203,0.001083215,0.00005083411,0.0000683479,0.0004231139,0.0005726134,0.0005732688,0.004033352,0.00948971],"study_design_scores_gemma":[0.987407,0.009015599,0.0003125175,0.0002821832,0.0003587796,0.00001135679,0.00001303461,0.0003346438,0.00008714765,0.0002436936,0.001916726,0.00001744568],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0186958,0.001815376,0.002182809,0.0006359671,0.0008456041,0.9688657,0.003704191,0.0003325779,0.002921912],"genre_scores_gemma":[0.01994807,0.0008915378,0.003660343,0.0007125536,0.0002312004,0.9721013,0.0006264683,0.00001399722,0.001814603],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.06255989,"threshold_uncertainty_score":0.2092836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1197287588459193,"score_gpt":0.5004709564464417,"score_spread":0.3807421976005224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}