{"id":"W2622606245","doi":"10.1038/ncomms15662","title":"NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology","keywords":"NEDD4; Cell biology; Messenger RNP; Ribonucleoprotein; Biology; Stress granule; Ubiquitin ligase; Messenger RNA; ESCRT; Homeostasis; RNA-binding protein; Regulator; Planarian; Cell; Cytoplasm; Endosome; RNA; Ubiquitin; Genetics; Regeneration (biology); Gene; Intracellular; Translation (biology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001568374,0.0002278262,0.0002139226,0.0002153396,0.000202832,0.0004415755,0.0002376493,0.0001787866,0.0007482212],"category_scores_gemma":[0.0001123,0.0001382189,0.000194975,0.0001115025,0.0003315788,0.0002260428,0.0002814815,0.0002648737,0.0002117593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003894794,"about_ca_system_score_gemma":0.0002707953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005409136,"about_ca_topic_score_gemma":0.000792652,"domain_scores_codex":[0.9998779,0.00002324487,0.00001356061,0.00003626314,0.00002757879,0.0000213671],"domain_scores_gemma":[0.9999211,0.000004651676,0.00002405912,0.00000707047,0.00001292373,0.00003022702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001826977,0.00001157942,0.001357468,0.00004811114,0.000009730445,0.0001312074,0.00002680755,0.0001151927,0.9940941,0.000611624,0.0001209334,0.003290507],"study_design_scores_gemma":[0.00004161826,0.0001871062,0.02663792,0.000007311938,0.00003188121,0.0005514658,0.00008459953,0.002903527,0.9556892,0.0003640391,0.01348796,0.00001337291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831783,0.004605682,0.007812318,0.0001572393,0.00007777801,0.00002733485,0.0005634371,0.0002184621,0.003359395],"genre_scores_gemma":[0.9912326,0.0009918187,0.003308477,0.0000600248,0.00001027095,0.0000190595,0.0005423413,0.0000276734,0.003807765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007482212,"threshold_uncertainty_score":0.002825916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0159915840058848,"score_gpt":0.30797110370004,"score_spread":0.2919795196941553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}