{"id":"W2622731939","doi":"10.1002/hon.2438_53","title":"A PHASE 2B RANDOMIZED STUDY OF SINGLE AGENT <scp>S</scp>ELINEXOR IN PATIENTS WITH RELAPSED/REFRACTORY DIFFUSE LARGE <scp>B</scp>‐CELL LYMPHOMA (<scp>DLBCL</scp>)","year":2017,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Neutropenia; Medicine; Internal medicine; Nausea; Adverse effect; Diffuse large B-cell lymphoma; Phases of clinical research; Anemia; Refractory (planetary science); Gastroenterology; Vomiting; Lymphoma; Febrile neutropenia; Oncology; Toxicity; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001068263,0.0009311539,0.004389109,0.0004255213,0.0004001129,0.00008037901,0.0006618886,0.0008571832,0.00003819194],"category_scores_gemma":[0.009616842,0.0006110336,0.0005889534,0.0003207339,0.000697091,0.00021332,0.0005217386,0.0004721553,0.0001640089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007535857,"about_ca_system_score_gemma":0.0003984922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001796378,"about_ca_topic_score_gemma":0.0002411505,"domain_scores_codex":[0.9933732,0.0009747844,0.001949461,0.001369778,0.0009471792,0.001385639],"domain_scores_gemma":[0.9868798,0.008386288,0.001900806,0.001674062,0.0004240837,0.0007349133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"nonrandomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.007782807,0.5439465,0.4238824,0.0002705138,0.001042659,0.005755744,0.004401333,0.000003519647,0.0003663393,0.0002815201,0.008292245,0.00397444],"study_design_scores_gemma":[0.763921,0.02235268,0.1862375,0.0002497095,0.00124643,0.0001675126,0.003337311,0.0001084836,0.002132122,0.000109021,0.02001711,0.000121132],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863166,0.001236944,0.00004436355,0.0001323535,0.0004868378,0.005072245,0.00008151511,0.0001523295,0.006476829],"genre_scores_gemma":[0.9961194,0.0002797091,0.0005806387,0.0005683167,0.000114034,0.001148857,0.0001585834,0.0001020228,0.0009284327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7561382,"threshold_uncertainty_score":0.9996341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02815762067654268,"score_gpt":0.3051412327820132,"score_spread":0.2769836121054705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}