{"id":"W2622897264","doi":"10.1002/hon.2437_57","title":"DYNAMO: a PHASE 2 STUDY DEMONSTRATING THE CLINICAL ACTIVITY OF DUVELISIB IN PATIENTS WITH DOUBLE‐REFRACTORY INDOLENT NON‐HODGKIN LYMPHOMA","year":2017,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Cégep de l'Outaouais; Jewish General Hospital","funders":"","keywords":"Medicine; Internal medicine; Adverse effect; Refractory (planetary science); Gastroenterology; Clinical endpoint; Regimen; Lymphoma; Surgery; Oncology; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001103248,0.0006436461,0.001123355,0.0002897909,0.0002088443,0.0006911847,0.0004619441,0.0004576845,0.002000412],"category_scores_gemma":[0.0004629898,0.0003342544,0.0005204441,0.0002457364,0.0004340624,0.000379192,0.0002862555,0.00105568,0.0003806852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005108921,"about_ca_system_score_gemma":0.0008356972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005762057,"about_ca_topic_score_gemma":0.00164131,"domain_scores_codex":[0.9998337,0.00007369569,0.00001095129,0.00002616016,0.00002064017,0.00003484472],"domain_scores_gemma":[0.9996665,0.0000555626,0.00006289862,0.00002476633,0.00002026484,0.0001700835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.521237,0.06034306,0.02734604,0.002391586,0.001592731,0.0006683402,0.0005904171,0.002299444,0.1224254,0.0003906554,0.005169034,0.2555464],"study_design_scores_gemma":[0.5551242,0.382891,0.04101427,0.00007584406,0.000620405,0.001236957,0.0001374247,0.00177324,0.008855373,0.000150246,0.008072619,0.00004830827],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947951,0.002253381,0.0003735267,0.000162375,0.00004610318,0.0007842572,0.0004279984,0.00007852024,0.001078727],"genre_scores_gemma":[0.9931329,0.001513319,0.001019194,0.0003722428,0.00006189207,0.0009174064,0.001423297,0.00001803905,0.001541701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002000412,"threshold_uncertainty_score":0.006692052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08567979818774954,"score_gpt":0.4524975538175632,"score_spread":0.3668177556298137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}