{"id":"W2622918134","doi":"10.1182/blood.v128.22.5083.5083","title":"Lef1 Is a Critical Mediator of Wnt/β-Catenin Signaling in T-Cell Acute Lymphoblastic Leukemia (T-ALL)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Wnt signaling pathway; Leukemia; Cancer research; Biology; Population; LRP6; Beta-catenin; WNT3A; Immunology; Signal transduction; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001096271,0.0003290733,0.0001907748,0.0003187216,0.0002556086,0.0003952184,0.0001824616,0.0003240238,0.001604683],"category_scores_gemma":[0.00008488993,0.0001300445,0.0001847668,0.000192619,0.0001827553,0.0002095755,0.0002429376,0.0005848901,0.0008725114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004445002,"about_ca_system_score_gemma":0.000217914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006765382,"about_ca_topic_score_gemma":0.0009700924,"domain_scores_codex":[0.9998788,0.00001200673,0.00001162963,0.00002996962,0.00003789013,0.00002961464],"domain_scores_gemma":[0.999925,0.000006377424,0.00002759747,0.000004666108,0.000008409342,0.00002777136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005899725,0.00001164642,0.0004561155,0.00003314269,0.000002052366,0.0001369891,0.00001422867,0.00003223707,0.9976152,0.0001437321,0.0000625172,0.001433194],"study_design_scores_gemma":[0.0000241497,0.0001196026,0.01709228,0.00001363296,0.00002083767,0.001441857,0.00006126102,0.0007110427,0.9708265,0.0000925681,0.009590548,0.000005740433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819227,0.007125564,0.005847198,0.0002556781,0.00004343149,0.00006263529,0.00154594,0.0002530211,0.002943857],"genre_scores_gemma":[0.9902321,0.001573179,0.001910637,0.00007609768,0.00001099169,0.00003696043,0.001749691,0.0000255748,0.004384926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001604683,"threshold_uncertainty_score":0.005368173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009876881711327822,"score_gpt":0.2274177365811152,"score_spread":0.2175408548697874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}