{"id":"W2623210482","doi":"10.1016/j.str.2017.05.013","title":"RBR Ubiquitin Transfer: Not Simply an “Open” and “Closed” Case?","year":2017,"lang":"en","type":"letter","venue":"Structure","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Ubiquitin; Chemistry; Computational biology; Cell biology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027913,0.0005850783,0.001101175,0.0002889467,0.002114455,0.003162635,0.001681039,0.02964516,0.005645671],"category_scores_gemma":[0.01216869,0.0003984732,0.0007226728,0.000293501,0.005519825,0.005414619,0.00173442,0.02465379,0.003495803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003297106,"about_ca_system_score_gemma":0.001466687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007105698,"about_ca_topic_score_gemma":0.0007736639,"domain_scores_codex":[0.9984902,0.0003925732,0.0001294453,0.0002340943,0.0004551117,0.0002983907],"domain_scores_gemma":[0.996888,0.001937508,0.0002402414,0.0002567008,0.0002764106,0.0004010988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004257413,0.00009656633,0.0006861564,0.0001054016,0.00003500802,0.00783495,0.00017809,0.0001676158,0.002195259,0.07595634,0.872614,0.03970479],"study_design_scores_gemma":[0.000290174,0.0001233412,0.0006242665,0.0001485832,0.00004377132,0.006620202,0.0003579045,0.00112392,0.003605969,0.2145845,0.7724047,0.00007263367],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001620515,0.004076207,0.0006418099,0.9754121,0.01366458,0.000007058357,0.00002665143,0.000046082,0.004505156],"genre_scores_gemma":[0.07360715,0.008926477,0.001603033,0.8043106,0.09299535,0.00007244378,0.0000882808,0.00006696396,0.01832977],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02964516,"threshold_uncertainty_score":0.02392226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02283580435037525,"score_gpt":0.2796820589585753,"score_spread":0.2568462546082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}