{"id":"W2623282334","doi":"","title":"Targeted delivery of CD4+ Th-APC’s stimulatory effect to CD8+ memory T cell responses via acquired synapse-composed pMHC I complexes","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CD80; Immunological synapse; T cell; Cell biology; Antigen-presenting cell; CD8; Immune system; Cytotoxic T cell; Internalization; Immunology; Chemistry; Biology; Cell; CD40; T-cell receptor; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001143239,0.0003353252,0.0002475756,0.0001449769,0.0001146587,0.0002396825,0.0001621839,0.0002495823,0.001960862],"category_scores_gemma":[0.0001158855,0.0001184353,0.0001553483,0.00005790107,0.0001853077,0.0001392138,0.0002291881,0.0005780961,0.000554983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002232639,"about_ca_system_score_gemma":0.0001452613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001718641,"about_ca_topic_score_gemma":0.0002445199,"domain_scores_codex":[0.9999022,0.00002406939,0.000004801379,0.0000134525,0.00001734205,0.00003813034],"domain_scores_gemma":[0.9999406,0.00001536521,0.000008809926,0.000008317684,0.000006548079,0.000020304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002561032,0.00009293888,0.00009819336,0.00006094674,0.000007003767,0.00006565856,0.00001452854,0.0001289751,0.9936393,0.0002037272,0.0001915786,0.005241061],"study_design_scores_gemma":[0.000122907,0.001040781,0.001068802,0.000008379895,0.00002212095,0.0002512269,0.00001202023,0.001471353,0.9928477,0.0000872515,0.003064103,0.000003342517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935312,0.001615459,0.002317111,0.0001908332,0.00004730187,0.00003575664,0.00005571875,0.00007348257,0.002133362],"genre_scores_gemma":[0.9955208,0.0005748574,0.001986331,0.00007110663,0.00003855426,0.00001917009,0.00009177247,0.00001564265,0.001681798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001960862,"threshold_uncertainty_score":0.006559789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02654660047234643,"score_gpt":0.3258496693819619,"score_spread":0.2993030689096154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}