{"id":"W2623551066","doi":"10.1002/cbic.201700244","title":"Inside Back Cover: A Tandem Enzymatic sp<sup>2</sup>‐C‐Methylation Process: Coupling in Situ S‐Adenosyl‐<scp>l</scp>‐Methionine Formation with Methyl Transfer (ChemBioChem 11/2017)","year":2017,"lang":"en","type":"paratext","venue":"ChemBioChem","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Gilead Sciences (Canada)","funders":"","keywords":"Tandem; In situ; Methionine; Methylation; Chemistry; Methyltransferase; Enzyme; Stereochemistry; Coupling (piping); Biochemistry; Amino acid; Organic chemistry; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0008779792,0.001360209,0.001364994,0.0004650973,0.0003648275,0.000365917,0.0009470487,0.002684766,0.0001702556],"category_scores_gemma":[0.0005344138,0.001397655,0.000416351,0.0006070224,0.0003291835,0.0001419176,0.0002000021,0.001106149,0.0007103789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000523437,"about_ca_system_score_gemma":0.001032135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005887048,"about_ca_topic_score_gemma":0.0001813651,"domain_scores_codex":[0.9946257,0.0001286606,0.001406083,0.001795424,0.0009356227,0.001108464],"domain_scores_gemma":[0.9960855,0.0001288758,0.00101818,0.001718629,0.0007233414,0.0003254747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004019961,0.0003828338,0.0001704186,0.003062955,0.0005885341,0.00001595349,0.002062141,0.0668209,0.8584893,0.00001037678,0.06710745,0.000887156],"study_design_scores_gemma":[0.003647769,0.0003331098,0.00009097167,0.001462008,0.0003096109,0.00008171275,0.0005715824,0.007030209,0.9518586,0.00004625766,0.0336801,0.0008880666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560162,0.0120566,0.008908951,0.0001714389,0.0004743065,0.002252305,0.0001457025,0.0000712122,0.01990332],"genre_scores_gemma":[0.964103,0.002582039,0.0006445279,0.0001343003,0.001257521,0.0003740349,0.009583428,0.0003035983,0.02101756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09336932,"threshold_uncertainty_score":0.9999149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01516182062129345,"score_gpt":0.2615315955413601,"score_spread":0.2463697749200667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}