{"id":"W2623577366","doi":"10.1158/1557-3265.ovcasymp16-ap32","title":"Abstract AP32: THE METHYLTRANSFERASE EZH2 IS A VULNERABLE TARGET IN SMALL CELL CARCINOMA OF THE OVARY, HYPERCALCEMIC TYPE (SCCOHT)","year":2017,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Biology; SMARCA4; EZH2; Cancer research; Chromatin; Chromatin remodeling; Histone methyltransferase; Cell cycle checkpoint; Cell biology; Cell cycle; Genetics; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009262962,0.0002553716,0.0002187523,0.0002365574,0.0001836439,0.0001948692,0.0001656869,0.0002764158,0.001489915],"category_scores_gemma":[0.000136356,0.00009234185,0.0002179501,0.0002654425,0.000181048,0.0001843901,0.0001764057,0.0003172933,0.0002458699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002435933,"about_ca_system_score_gemma":0.0001665224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000411113,"about_ca_topic_score_gemma":0.0005593619,"domain_scores_codex":[0.9999281,0.000004867164,0.00000591375,0.00002237877,0.00002590949,0.00001281559],"domain_scores_gemma":[0.999949,0.000006044183,0.00001646069,0.000004481365,0.00000944864,0.00001464343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002491244,0.00001533465,0.00406296,0.00009675196,0.00001753467,0.0003315223,0.00001411456,0.00005580494,0.9919044,0.00005864174,0.000120444,0.00307332],"study_design_scores_gemma":[0.00006715656,0.0006279337,0.08532266,0.0000122357,0.0001062785,0.005174545,0.000110058,0.001409602,0.8990486,0.0002202355,0.007889634,0.00001099009],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9941458,0.003064689,0.001498212,0.0001534073,0.00002770924,0.00002583379,0.0004243207,0.00003407014,0.0006259572],"genre_scores_gemma":[0.995531,0.0009776946,0.0009978667,0.00008515835,0.00001453862,0.00002627903,0.000710958,0.000007869542,0.00164849],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001489915,"threshold_uncertainty_score":0.00498426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1792497800052143,"score_gpt":0.461124827851324,"score_spread":0.2818750478461097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}