{"id":"W2624062961","doi":"10.1002/dvdy.24532","title":"Xenopus pitx3 target genes lhx1 and xnr5 are identified using a novel three‐fluor flow cytometry–based analysis of promoter activation and repression","year":2017,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Flow cytometry; Transcription factor; Somitogenesis; Promoter; Xenopus; Cell biology; Gene; Molecular biology; Genetics; Embryonic stem cell; Gene expression; Somite","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003243984,0.0003826808,0.000242177,0.000540371,0.0003946217,0.0004760605,0.0004522055,0.0005265639,0.002128955],"category_scores_gemma":[0.0002032664,0.0001953239,0.0004196079,0.0002330334,0.0004878601,0.0003147526,0.0004388267,0.0008443837,0.0005342975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000887115,"about_ca_system_score_gemma":0.0003768925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001017472,"about_ca_topic_score_gemma":0.001600884,"domain_scores_codex":[0.9997596,0.00001982691,0.00001329842,0.00009264692,0.00007571292,0.00003886874],"domain_scores_gemma":[0.9997907,0.00006264482,0.00006567119,0.00001900827,0.00002785996,0.00003406801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002555019,0.000006567711,0.0001891849,0.00001666796,0.000002398099,0.00001369598,0.00001004425,0.00004365155,0.9982769,0.0001209747,0.0000305331,0.00126377],"study_design_scores_gemma":[0.000009176493,0.00003067361,0.002822823,0.000004042117,0.00000669872,0.0001824267,0.00001319331,0.002660563,0.9931412,0.00007750975,0.001043604,0.000008001889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7066436,0.001005888,0.2843613,0.000386641,0.00007857792,0.0002006517,0.001869477,0.001368116,0.004085731],"genre_scores_gemma":[0.7938168,0.0008906898,0.1981229,0.0003512465,0.00003069576,0.0004391331,0.001558859,0.0001839267,0.004605721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002128955,"threshold_uncertainty_score":0.007122099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01737859791796643,"score_gpt":0.2663952856117062,"score_spread":0.2490166876937398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}