{"id":"W2624207812","doi":"10.1002/hon.2438_72","title":"PHASE I/II CLINICAL TRIAL OF AN ACTIVATED WHOLE TUMOR CELL VACCINE FOLLOWED BY TRANSFER OF IMMUNE T CELLS IN PATIENTS WITH MANTLE CELL LYMPHOMA","year":2017,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Leukapheresis; Mantle cell lymphoma; Autologous stem-cell transplantation; Internal medicine; Vaccination; Rash; Minimal residual disease; Adverse effect; Peripheral blood mononuclear cell; Oncology; Gastroenterology; Immunology; Lymphoma; CD34; Bone marrow; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009364089,0.0002768172,0.001968696,0.0001347439,0.0001004514,0.0000090637,0.0004914622,0.0004884821,0.001169525],"category_scores_gemma":[0.0001841691,0.0001904633,0.0002749032,0.0001615698,0.0004098094,0.0001043289,0.0001359883,0.000442279,0.00001527692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009904312,"about_ca_system_score_gemma":0.0002950893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008299757,"about_ca_topic_score_gemma":0.00002110479,"domain_scores_codex":[0.996612,0.0004899463,0.001382075,0.0005503123,0.000448725,0.0005169048],"domain_scores_gemma":[0.9976403,0.0004714473,0.0004719403,0.0009298238,0.0002056085,0.000280919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.2973002,0.08091693,0.008981935,0.000145078,0.00007647132,0.0003242724,0.0001085993,5.276476e-7,0.6048338,0.000008800189,0.0004726283,0.006830712],"study_design_scores_gemma":[0.3942431,0.07639873,0.007394827,0.00004377659,0.00008520785,0.00001181236,0.00005204169,0.00003784027,0.5185124,0.00001280957,0.003049517,0.0001579033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946449,0.00005054115,0.00001761664,0.000267269,0.0001931683,0.001909868,0.00004835554,0.0000243704,0.002843854],"genre_scores_gemma":[0.9985562,0.00003636137,0.0003524089,0.00008801849,0.00004375112,0.00005373742,0.00008218078,0.00003612828,0.0007512427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09694286,"threshold_uncertainty_score":0.9997435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04352436042808341,"score_gpt":0.3849561013122416,"score_spread":0.3414317408841582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}