{"id":"W2624230523","doi":"10.1073/pnas.1701201114","title":"Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Seventh Framework Programme; European Research Council; Ministry of Agriculture and Rural Development; Israel Science Foundation","keywords":"Cholinergic; Forebrain; Neuroscience; Vesicular acetylcholine transporter; Epileptogenesis; Epilepsy; Biology; Central nervous system; Choline acetyltransferase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001054637,0.0001526581,0.000135389,0.0002969605,0.0001137231,0.0002286017,0.00009064313,0.0001828622,0.0008428098],"category_scores_gemma":[0.0001078925,0.0001628025,0.0001870795,0.0001010694,0.0002336354,0.0001238451,0.0001162505,0.000427902,0.0003003797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002213512,"about_ca_system_score_gemma":0.00009066241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001588715,"about_ca_topic_score_gemma":0.0003064697,"domain_scores_codex":[0.9999177,0.000008245827,0.000008641008,0.00002474526,0.0000175062,0.00002314393],"domain_scores_gemma":[0.9998555,0.00001426441,0.00006834455,0.00001221359,0.00001193159,0.00003776609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000141526,0.00001208404,0.00059415,0.000007983433,0.000003758737,0.00004611619,0.000009852273,0.00002628423,0.9985315,0.00005708754,0.00002044283,0.0005491545],"study_design_scores_gemma":[0.00001847856,0.0003532613,0.04213997,0.000007639143,0.00003149319,0.0008664382,0.00006533343,0.000938817,0.9536587,0.0001722438,0.001738597,0.000009002055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967783,0.0004012196,0.001775717,0.00005215614,0.00001311043,0.000008344607,0.0002336393,0.0000515541,0.0006859523],"genre_scores_gemma":[0.9960431,0.0003056364,0.001489214,0.00003623682,0.000004856768,0.00002479962,0.0002734604,0.00001846642,0.001804167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008428098,"threshold_uncertainty_score":0.002819479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01757092543621518,"score_gpt":0.2959788575316283,"score_spread":0.2784079320954131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}