{"id":"W2624535566","doi":"10.1002/hon.2437_81","title":"THE 23‐GENE GENE EXPRESSION‐BASED ASSAY DOES NOT PREDICT INTERIM PET SCAN RESULTS AFTER ABVD IN ADVANCED STAGE CLASSICAL HODGKIN LYMPHOMA IN THE US INTERGROUP S0816 TRIAL","year":2017,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"ABVD; Medicine; Oncology; Clinical endpoint; Lymphoma; Internal medicine; Context (archaeology); Stage (stratigraphy); Interim analysis; Dacarbazine; Surrogate endpoint; Clinical trial; Nuclear medicine; Chemotherapy; Biology; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001546838,0.0004116951,0.001097453,0.0001161444,0.0003040719,0.000141113,0.000762777,0.000403246,0.00007331849],"category_scores_gemma":[0.002472809,0.0001714754,0.0002870566,0.0001155128,0.0007047793,0.0001387804,0.0003733875,0.0003779964,0.000039267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006754313,"about_ca_system_score_gemma":0.0003167783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000850274,"about_ca_topic_score_gemma":0.001362489,"domain_scores_codex":[0.995728,0.001148521,0.00110197,0.0008153468,0.0004735372,0.0007325795],"domain_scores_gemma":[0.9951399,0.002772259,0.0005020502,0.001319479,0.00006643927,0.0001998794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6011412,0.02862645,0.2229427,0.0001467347,0.0003082319,0.05737877,0.001555716,0.00002217739,0.0128877,0.00215165,0.004696857,0.06814175],"study_design_scores_gemma":[0.2154378,0.009510658,0.6866232,0.0005450196,0.0001416947,0.0007784921,0.0004912306,0.0005876212,0.04961932,0.0003704259,0.03538132,0.0005132036],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799646,0.000208909,0.00003856674,0.01535305,0.0008450518,0.001640924,0.00009306923,0.00005060304,0.001805235],"genre_scores_gemma":[0.9941209,0.000168523,0.001165732,0.001820754,0.0002294286,0.00202881,0.00005824581,0.00002343838,0.0003841616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4636804,"threshold_uncertainty_score":0.6992562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0370597856809882,"score_gpt":0.3473945094879564,"score_spread":0.3103347238069682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}