{"id":"W2624535566","doi":"10.1002/hon.2437_81","title":"THE 23‐GENE GENE EXPRESSION‐BASED ASSAY DOES NOT PREDICT INTERIM PET SCAN RESULTS AFTER ABVD IN ADVANCED STAGE CLASSICAL HODGKIN LYMPHOMA IN THE US INTERGROUP S0816 TRIAL","year":2017,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"ABVD; Medicine; Oncology; Clinical endpoint; Lymphoma; Internal medicine; Context (archaeology); Stage (stratigraphy); Interim analysis; Dacarbazine; Surrogate endpoint; Clinical trial; Nuclear medicine; Chemotherapy; Biology; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004742295,0.0007708788,0.001292153,0.0002307145,0.0001746988,0.0007391523,0.0004350936,0.0006272822,0.001336406],"category_scores_gemma":[0.002973785,0.0002337401,0.001037702,0.0003595234,0.0006029828,0.0006353232,0.0003572942,0.001265265,0.0003263477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005586058,"about_ca_system_score_gemma":0.0004519728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002135334,"about_ca_topic_score_gemma":0.0007719256,"domain_scores_codex":[0.998481,0.001019052,0.0001047659,0.0001652244,0.0001451233,0.00008497328],"domain_scores_gemma":[0.9982166,0.0006844032,0.0005440807,0.0002375921,0.00009681339,0.0002205059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7279857,0.001832381,0.161657,0.0009181811,0.004482775,0.00021461,0.000316428,0.005402022,0.02113614,0.0002694974,0.002287351,0.0734979],"study_design_scores_gemma":[0.1925531,0.2384978,0.5151262,0.0005251104,0.006869153,0.001526027,0.0002536439,0.01310876,0.01511503,0.00350963,0.01274212,0.0001735084],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996905,0.001507194,0.0002065993,0.0001612999,0.00003559068,0.000137204,0.0003897409,0.00001166659,0.0006458037],"genre_scores_gemma":[0.9971374,0.0003501605,0.0004777455,0.0002534171,0.00005078541,0.000297741,0.001003067,0.000009165962,0.0004203934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004742295,"threshold_uncertainty_score":0.02507997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0370597856809882,"score_gpt":0.3473945094879564,"score_spread":0.3103347238069682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}