{"id":"W2624747407","doi":"10.3390/metabo7020028","title":"Metabolomic Profiling of Bile Acids in Clinical and Experimental Samples of Alzheimer’s Disease","year":2017,"lang":"en","type":"article","venue":"Metabolites","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":154,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University; Alzheimer’s Research UK; European Regional Development Fund; Invest Northern Ireland","keywords":"Tauroursodeoxycholic acid; Cholic acid; Lithocholic acid; Taurocholic acid; Bile acid; Chemistry; Endogeny; Internal medicine; Pathophysiology; Glycocholic acid; Chenodeoxycholic acid; Endocrinology; Biochemistry; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002302798,0.0003263598,0.0004375056,0.0009423757,0.0002411459,0.0003570069,0.0001068254,0.000309287,0.0007377241],"category_scores_gemma":[0.0004376847,0.0001120723,0.0002042187,0.0006676592,0.0002555677,0.000113993,0.0002805237,0.0002710985,0.0002226585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001385637,"about_ca_system_score_gemma":0.0001684175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007857888,"about_ca_topic_score_gemma":0.001016534,"domain_scores_codex":[0.9998134,0.00004161352,0.00002212623,0.00004589643,0.0000489137,0.00002805997],"domain_scores_gemma":[0.9998206,0.00002292857,0.00004326798,0.00001697075,0.00006594069,0.00003033232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007606558,0.0002188703,0.06899714,0.0002927233,0.0002912814,0.0007773497,0.0003229912,0.0001384133,0.8982488,0.0001172941,0.0005492332,0.02243942],"study_design_scores_gemma":[0.0001290149,0.002600521,0.8281339,0.00006024312,0.0003898437,0.004955757,0.000668716,0.001218085,0.1548397,0.0003342055,0.006626084,0.00004398009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934478,0.003013314,0.001070664,0.00008138466,0.00003823611,0.00004373732,0.001649223,0.00003436283,0.0006211849],"genre_scores_gemma":[0.9905732,0.002022763,0.002371948,0.0002247136,0.00004166388,0.00009916354,0.003550336,0.00002444661,0.001091813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009423757,"threshold_uncertainty_score":0.00246793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06345430430307178,"score_gpt":0.3651405629148123,"score_spread":0.3016862586117406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}