{"id":"W2624748903","doi":"10.1182/blood.v128.22.1974.1974","title":"Combined DNA and Transcriptome Sequencing Reveals Discrete Subtypes of Myelodysplasia","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Biology; CD34; Transcriptome; Myelodysplastic syndromes; Proportional hazards model; Myeloid; Survival analysis; Bone marrow; Gene; NPM1; Cancer research; Genetics; Immunology; Gene expression; Molecular biology; Stem cell; Internal medicine; Medicine; Karyotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001914939,0.0001651429,0.0002405761,0.0005875474,0.0001441018,0.0003700084,0.000130544,0.0002378257,0.0004879129],"category_scores_gemma":[0.0004378546,0.00008948943,0.0001959613,0.0004397668,0.0001539798,0.00008936918,0.000224399,0.0001641482,0.0001810832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001228765,"about_ca_system_score_gemma":0.00009828265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003641562,"about_ca_topic_score_gemma":0.0008608289,"domain_scores_codex":[0.9998052,0.00003240608,0.00001879484,0.00006700649,0.00004497385,0.00003174685],"domain_scores_gemma":[0.9998147,0.00005348142,0.00006093719,0.00002041683,0.00002785928,0.00002264295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004856043,0.00003983112,0.3334233,0.00008521479,0.0001179158,0.0004487056,0.0001956925,0.0003836358,0.6477042,0.00009297401,0.0002110515,0.01681189],"study_design_scores_gemma":[0.00001971385,0.0001999792,0.9513577,0.00001776564,0.000120077,0.002188095,0.0002272766,0.002380687,0.04206189,0.0002184962,0.001198861,0.000009408043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982116,0.0002937025,0.0008165047,0.00002116125,0.000002083797,0.000006441825,0.0004549862,0.00001084116,0.000182643],"genre_scores_gemma":[0.9973263,0.0001077972,0.00122802,0.00002258827,0.00000607983,0.00001358075,0.001081865,0.000004318702,0.0002095238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005875474,"threshold_uncertainty_score":0.001632273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01724888305884434,"score_gpt":0.2658266640058967,"score_spread":0.2485777809470523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}