{"id":"W2624840049","doi":"10.3390/brainsci7060069","title":"Contribution of the Degeneration of the Neuro-Axonal Unit to the Pathogenesis of Multiple Sclerosis","year":2017,"lang":"en","type":"review","venue":"Brain Sciences","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Cameco (Canada)","funders":"Office of Research and Development; Health Science Center, University of Tennessee; U.S. Department of Veterans Affairs","keywords":"Neurodegeneration; Multiple sclerosis; Pathogenesis; Neuroscience; Medicine; Demyelinating disease; Disease; Central nervous system; Axonal degeneration; Biology; Pathology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004782476,0.0005710266,0.0009687353,0.002649951,0.0003072409,0.0009266091,0.0006127023,0.0008461367,0.002588461],"category_scores_gemma":[0.0006836678,0.0001880833,0.0003737003,0.002630498,0.000571963,0.001158287,0.0006959898,0.001117612,0.001188199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005469686,"about_ca_system_score_gemma":0.001279792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00109087,"about_ca_topic_score_gemma":0.001692013,"domain_scores_codex":[0.9998158,0.00003527992,0.00003960006,0.00003067006,0.00006393854,0.00001489354],"domain_scores_gemma":[0.9996749,0.0001574613,0.0000539426,0.000009372353,0.00007721639,0.00002702677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000062504,0.00004977355,0.0003169805,0.03289048,0.0001118499,0.0003121697,0.0001038539,0.0002234848,0.001767449,0.004135586,0.01764921,0.9423767],"study_design_scores_gemma":[0.00001445449,0.00009128178,0.00184953,0.01062129,0.0001933254,0.002818488,0.0001609504,0.00005615887,0.0005906731,0.003051845,0.9805284,0.0000236126],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007321406,0.9992349,0.00003509738,0.0001628477,0.000089236,0.000001591652,0.000006172117,0.000002317031,0.0003945538],"genre_scores_gemma":[0.0003875606,0.9992624,0.00005436605,0.0000687119,0.00007408103,0.000001688077,0.000005887463,3.807078e-7,0.000145005],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002649951,"threshold_uncertainty_score":0.008659244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3828473231421801,"score_gpt":0.4219780931056595,"score_spread":0.03913076996347942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}