{"id":"W2624972845","doi":"10.2147/itt.s131662","title":"CD8<sup>+</sup> memory T-cell inflation renders compromised CD4<sup>+</sup> T-cell-dependent CD8<sup>+</sup> T-cell immunity via naïve T-cell anergy","year":2017,"lang":"de","type":"article","venue":"ImmunoTargets and Therapy","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"CD8; Biology; T cell; Cytotoxic T cell; Molecular biology; IL-2 receptor; Immunology; Antigen; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","scholarly_communication","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"category_scores_codex":[0.006319787,0.008713901,0.008964743,0.002977616,0.01243075,0.002498958,0.01000598,0.009499623,0.008968782],"category_scores_gemma":[0.0005732688,0.008669133,0.004198357,0.001852704,0.007616189,0.0032568,0.004240366,0.009079397,0.009041533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001829906,"about_ca_system_score_gemma":0.002338264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003108407,"about_ca_topic_score_gemma":0.0009914091,"domain_scores_codex":[0.9632068,0.007373474,0.008977239,0.008171882,0.002416228,0.009854374],"domain_scores_gemma":[0.9724959,0.00287882,0.007757063,0.01243006,0.002654621,0.001783523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01393174,0.01104529,0.0009800557,0.001226646,0.006240345,0.0007153364,0.01334259,0.001976144,0.9078616,0.0005662347,0.0273922,0.01472183],"study_design_scores_gemma":[0.06068648,0.006244427,0.001586598,0.0009588181,0.002593247,0.0008867534,0.00229445,0.00308165,0.3090492,0.001057456,0.6011018,0.01045923],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7222965,0.2386944,0.0007146901,0.001465303,0.009308115,0.006487972,0.001756337,0.00138267,0.01789395],"genre_scores_gemma":[0.8177479,0.1149283,0.00104858,0.001589956,0.002041325,0.0008163952,0.006945754,0.001471497,0.05341029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5988125,"threshold_uncertainty_score":0.9985365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504890613580376,"score_gpt":0.2296633367682991,"score_spread":0.2146144306324953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}