{"id":"W2624972845","doi":"10.2147/itt.s131662","title":"CD8<sup>+</sup> memory T-cell inflation renders compromised CD4<sup>+</sup> T-cell-dependent CD8<sup>+</sup> T-cell immunity via naïve T-cell anergy","year":2017,"lang":"de","type":"article","venue":"ImmunoTargets and Therapy","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"CD8; Biology; T cell; Cytotoxic T cell; Molecular biology; IL-2 receptor; Immunology; Antigen; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001879812,0.0005370495,0.000327928,0.00029071,0.0001273981,0.000311714,0.0002307301,0.0003751624,0.003203831],"category_scores_gemma":[0.0001451277,0.0001765387,0.0001908956,0.00009221373,0.0003648229,0.0003416359,0.0002480113,0.001109085,0.0007223747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002005122,"about_ca_system_score_gemma":0.0001311739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001743612,"about_ca_topic_score_gemma":0.0002830782,"domain_scores_codex":[0.9997886,0.00003587357,0.00002834614,0.00005144516,0.00004062718,0.00005515309],"domain_scores_gemma":[0.9996505,0.00005101051,0.0001016933,0.00004271578,0.00002283085,0.0001312292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003216941,0.00007738556,0.0002506565,0.00002850096,0.000003676048,0.00009330233,0.00001541157,0.00005465647,0.9980666,0.00009491039,0.00006107031,0.000932107],"study_design_scores_gemma":[0.00007479865,0.001422957,0.006450098,0.00001776952,0.00003765049,0.001218355,0.00007323343,0.00159341,0.9863787,0.0001441674,0.002579648,0.000009229087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966048,0.0003184363,0.001602745,0.00007817681,0.00002773802,0.00002102937,0.0002511485,0.0001507643,0.0009452013],"genre_scores_gemma":[0.9946433,0.0001575889,0.001329543,0.00007337607,0.00002183079,0.00003856858,0.0002925527,0.00006480048,0.003378481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003203831,"threshold_uncertainty_score":0.01071793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504890613580376,"score_gpt":0.2296633367682991,"score_spread":0.2146144306324953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}