{"id":"W2625016901","doi":"10.1074/jbc.m116.765941","title":"Cry6Aa1, a Bacillus thuringiensis nematocidal and insecticidal toxin, forms pores in planar lipid bilayers at extremely low concentrations and without the need of proteolytic processing","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bacillus thuringiensis; Toxin; Chemistry; Microbiology; Biochemistry; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002809546,0.0002987492,0.0002525036,0.0001860779,0.0001826403,0.0005062381,0.0002432496,0.0004247044,0.0005728413],"category_scores_gemma":[0.0003912357,0.0001733462,0.0001775995,0.000150885,0.0003917042,0.0005574817,0.000461392,0.0004720546,0.0009052775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002394968,"about_ca_system_score_gemma":0.0002112286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002683362,"about_ca_topic_score_gemma":0.0002878966,"domain_scores_codex":[0.9997552,0.00004393683,0.00001212112,0.00003508844,0.000113857,0.00003977661],"domain_scores_gemma":[0.9997513,0.00004140012,0.00007569886,0.00002234945,0.00004936889,0.00005990505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005919511,0.000009685202,0.0001934875,0.00005224438,0.000004688784,0.00002689546,0.00001495734,0.00005339668,0.9973647,0.0001570994,0.0001168858,0.001946832],"study_design_scores_gemma":[0.00002423156,0.0001447491,0.00311078,0.000009263849,0.000009855346,0.0007197516,0.00005771988,0.001262038,0.9897228,0.0002241298,0.004702824,0.00001178181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758859,0.00399922,0.01417263,0.0005370118,0.00008127295,0.00005738813,0.0007263682,0.0003369367,0.004203181],"genre_scores_gemma":[0.9872764,0.001823308,0.005675301,0.0001608319,0.00001893436,0.00002014227,0.001202417,0.00005310071,0.003769531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005728413,"threshold_uncertainty_score":0.001916289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01735342567653573,"score_gpt":0.2526314095100803,"score_spread":0.2352779838335446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}