{"id":"W2625158686","doi":"10.71781/26305","title":"Development of a retroviral strategy that efficiently creates nested chromosomal deletions in mouse embryonic stem cells and its exploitation for functional genomics","year":2007,"lang":"en","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Génome Québec; George Washington University","keywords":"Embryonic stem cell; Biology; Stem cell; Computational biology; Genomics; Genetics; Cell biology; Genome; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006550945,0.0007425893,0.0003625114,0.0008294343,0.0004555458,0.0007226239,0.001062426,0.0006834942,0.001809489],"category_scores_gemma":[0.000259887,0.0006203463,0.0007200543,0.0003106626,0.0004332152,0.0004062424,0.0005051565,0.001572455,0.001573002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006429646,"about_ca_system_score_gemma":0.0009227686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00239633,"about_ca_topic_score_gemma":0.004169211,"domain_scores_codex":[0.9996617,0.00003409585,0.00003823739,0.00006802681,0.000147494,0.00005044468],"domain_scores_gemma":[0.9997578,0.00005370535,0.00005298797,0.00005347919,0.00003619404,0.00004569478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001854726,0.0000247672,0.0000753241,0.00001939054,0.000006176096,0.00005514325,0.00002137617,0.00009106476,0.9956295,0.0006708319,0.00009032998,0.003297464],"study_design_scores_gemma":[0.00001578836,0.00007072551,0.0005124492,0.00000698723,0.00002703364,0.0002590938,0.00001067113,0.0007056657,0.9911902,0.00006527026,0.00712828,0.000007781441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4772587,0.002288159,0.4946796,0.0007556847,0.0003238585,0.001833032,0.003017733,0.003825539,0.01601772],"genre_scores_gemma":[0.659292,0.002705239,0.2955081,0.000352166,0.00004378469,0.0008395977,0.006447021,0.0009335641,0.03387847],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00239633,"threshold_uncertainty_score":0.006053329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009819645730056472,"score_gpt":0.213021888909303,"score_spread":0.2032022431792465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}