{"id":"W2625662684","doi":"10.1503/cmaj.170074","title":"Assessing the safety and immunogenicity of recombinant vesicular stomatitis virus Ebola vaccine in healthy adults: a randomized clinical trial","year":2017,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Canadian Science Centre for Human and Animal Health; Izaak Walton Killam Health Centre","funders":"Medical Research and Materiel Command; Canadian Institutes of Health Research; Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense; Oak Ridge Institute for Science and Education; Canadian Immunization Research Network; Dalhousie University; Battelle; Public Health Agency; Public Health Agency of Canada; U.S. Department of Energy; U.S. Department of Defense","keywords":"Immunogenicity; Ebola virus; Medicine; Ebola vaccine; Vesicular stomatitis virus; Randomized controlled trial; Virology; Clinical trial; Vesicular Stomatitis; Ebolavirus; Recombinant DNA; Immunology; Virus; Internal medicine; Biology; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004511071,0.001746715,0.003610163,0.000468023,0.0006522963,0.001413106,0.0009441102,0.003341228,0.007516833],"category_scores_gemma":[0.004526816,0.0007622314,0.002447818,0.0004740192,0.00136344,0.00134867,0.0004717455,0.002405389,0.0009342373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007291232,"about_ca_system_score_gemma":0.001562405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006809495,"about_ca_topic_score_gemma":0.001179409,"domain_scores_codex":[0.9980076,0.00119622,0.0001888981,0.0002929289,0.0001267272,0.0001876364],"domain_scores_gemma":[0.9974995,0.0008361755,0.0006676758,0.0002067653,0.0002375573,0.0005522973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9884063,0.003348197,0.0003876642,0.0006436357,0.0008304296,0.00002180366,0.00002595652,0.00007911774,0.0007647016,0.0000390941,0.0002894813,0.005163695],"study_design_scores_gemma":[0.9505119,0.04720258,0.0009859892,0.00005156716,0.0005301698,0.00001390427,0.00001387397,0.0001376455,0.0001275634,0.00008122215,0.000334855,0.000008772837],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9589679,0.01308776,0.001221976,0.001512916,0.001541423,0.01914918,0.001517594,0.0001509251,0.002850421],"genre_scores_gemma":[0.9661661,0.005685894,0.002151049,0.002314397,0.001234635,0.01900427,0.0009831875,0.00002124181,0.002439119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007516833,"threshold_uncertainty_score":0.02514631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02770332975105257,"score_gpt":0.3924936291337212,"score_spread":0.3647902993826686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}