{"id":"W2626196197","doi":"10.1016/j.jacc.2017.04.051","title":"Association of Triglyceride-Related Genetic Variants With Mitral Annular Calcification","year":2017,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill Genome Centre; McGill University Health Centre","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Hjartavernd","keywords":"Medicine; Odds ratio; Mendelian randomization; Internal medicine; Triglyceride; Confidence interval; Pleiotropy; Cardiology; Cholesterol; Endocrinology; Genetics; Genetic variants; Genotype; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007683248,0.0007169519,0.0005276453,0.001333502,0.0005294262,0.0008716272,0.000616774,0.001226391,0.00405721],"category_scores_gemma":[0.003333386,0.0004081822,0.001244796,0.001616014,0.000541922,0.0004302215,0.0005623836,0.001331194,0.0003402303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001857206,"about_ca_system_score_gemma":0.0002461115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002556649,"about_ca_topic_score_gemma":0.001919628,"domain_scores_codex":[0.9989863,0.000319425,0.000186346,0.0002645234,0.0001346318,0.0001087148],"domain_scores_gemma":[0.9971264,0.001123959,0.0009007215,0.000318688,0.0002280636,0.0003021263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002198128,0.0001697419,0.9797069,0.00004348699,0.001746242,0.001763429,0.0001871338,0.0003698126,0.009063757,0.0004750385,0.0002681961,0.004008314],"study_design_scores_gemma":[0.0001067721,0.0002320777,0.991768,0.00002464697,0.0009264888,0.002349828,0.0001722334,0.002423331,0.001082443,0.0005766156,0.0003112249,0.00002641244],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973907,0.0004795526,0.0008660394,0.0001576891,0.00004571397,0.000006426621,0.0002531694,0.00002570519,0.0007751505],"genre_scores_gemma":[0.9992243,0.00008013118,0.0003090866,0.0000219749,0.00003473884,0.000003399467,0.0001020062,0.000008704826,0.000215624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00405721,"threshold_uncertainty_score":0.01357269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0080402972475881,"score_gpt":0.2516916101365707,"score_spread":0.2436513128889826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}