{"id":"W2626568439","doi":"10.1158/1078-0432.ccr-15-1636","title":"Molecular Pathways: Targeting the Microenvironment of Liver Metastases","year":2017,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Cancer Institute","keywords":"Colorectal cancer; Paracrine signalling; Medicine; Cancer; Autocrine signalling; Cancer research; Metastasis; Gastrointestinal tract; Tumor microenvironment; Liver cancer; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.01273854,0.0003110131,0.003386844,0.0001910351,0.0003476695,0.00003879264,0.001148244,0.0005225784,0.001064594],"category_scores_gemma":[0.005743389,0.0001689742,0.001138085,0.0002199121,0.003016633,0.00003205732,0.0009360005,0.003067398,0.0002845769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003000109,"about_ca_system_score_gemma":0.003422272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004327298,"about_ca_topic_score_gemma":0.00001776873,"domain_scores_codex":[0.9923252,0.003268167,0.00150456,0.0007076734,0.001396892,0.0007974949],"domain_scores_gemma":[0.9920302,0.004960203,0.0005751046,0.001707935,0.0003560277,0.0003705399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000133668,0.0003921137,0.0007747764,0.01307264,0.001240576,0.0004938145,0.00003626088,1.13435e-7,0.00001384191,0.0001192069,0.009779979,0.973943],"study_design_scores_gemma":[0.000556091,0.0006067319,0.0002843015,0.008879046,0.001710991,0.00002346004,0.00003356606,0.00001090245,0.00002085977,0.00004695593,0.9876897,0.000137364],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008442138,0.994184,0.00001001317,0.0004378529,0.0001365682,0.002330424,0.0001573436,0.00001003127,0.001889554],"genre_scores_gemma":[0.0003387269,0.9958545,0.0002505055,0.00007669371,0.0006326602,0.0006994968,0.00005996761,0.0000641834,0.002023294],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9779097,"threshold_uncertainty_score":0.9998485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6281386272263334,"score_gpt":0.6151416007931797,"score_spread":0.0129970264331537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}