{"id":"W2626753829","doi":"10.1186/s13104-017-2526-8","title":"A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy","year":2017,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland; University of Melbourne; University of Virginia","keywords":"Drosophila melanogaster; RNA interference; Biology; Dopaminergic; Cell biology; Phenotype; Model organism; Aromatic L-amino acid decarboxylase; Kinase; Gene expression; Gene; Genetics; Dopamine; RNA; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001317416,0.0007042892,0.0002466638,0.0005428215,0.0003245918,0.0002865963,0.0004364658,0.000722584,0.003202334],"category_scores_gemma":[0.0001175609,0.0002474649,0.0004092937,0.0002223203,0.0003516482,0.0002519879,0.0003880918,0.000856679,0.0007442158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005535727,"about_ca_system_score_gemma":0.0002685271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001279131,"about_ca_topic_score_gemma":0.002330864,"domain_scores_codex":[0.9998462,0.00001593357,0.00002386571,0.00005079049,0.00004092035,0.00002233826],"domain_scores_gemma":[0.9997987,0.00003516551,0.00007338655,0.00001760671,0.00001303505,0.00006217062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001653835,0.00004334933,0.0001719749,0.00006773682,0.000008889206,0.0001763436,0.00002377036,0.00007906355,0.9980123,0.0002510022,0.00009405762,0.0009060382],"study_design_scores_gemma":[0.0001496738,0.0004925781,0.007160213,0.00005278354,0.00005308056,0.0008822227,0.00007229228,0.002532604,0.9768637,0.0001569577,0.01156571,0.00001820284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835086,0.001486509,0.005272242,0.0003435042,0.0001173942,0.0002000222,0.003409553,0.000325799,0.005336314],"genre_scores_gemma":[0.9735762,0.0009748651,0.005450951,0.0001625003,0.00001951941,0.0002389021,0.002541409,0.0001555521,0.01688009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003202334,"threshold_uncertainty_score":0.0107128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1513375223489333,"score_gpt":0.4008905048330407,"score_spread":0.2495529824841074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}