{"id":"W2626911737","doi":"10.1021/cen-09449-notw6","title":"CRISPR knocks out HIV in cells","year":2016,"lang":"en","type":"article","venue":"C&EN Global Enterprise","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Human immunodeficiency virus (HIV); Virology; Biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009424481,0.000669847,0.000681515,0.0007071624,0.000657382,0.001763639,0.001209114,0.001617199,0.007203783],"category_scores_gemma":[0.001196643,0.000635816,0.000722845,0.0004946101,0.0008636165,0.0006282494,0.0009382403,0.003066883,0.005321659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007316801,"about_ca_system_score_gemma":0.0007927808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001948935,"about_ca_topic_score_gemma":0.003078475,"domain_scores_codex":[0.9986166,0.0001621307,0.0001343091,0.000289684,0.0006457167,0.0001516057],"domain_scores_gemma":[0.9993229,0.0001988024,0.00008265499,0.0001757747,0.0001165448,0.0001033285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001617207,0.00007740207,0.0005247043,0.0004496537,0.00008757673,0.0007633783,0.000302395,0.001151541,0.9132397,0.01711594,0.02658411,0.03954197],"study_design_scores_gemma":[0.0001028476,0.0002673979,0.001050523,0.0001497258,0.00007961318,0.001475163,0.0001211459,0.003619138,0.5436194,0.003135486,0.446298,0.00008142144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2355647,0.01911784,0.4936679,0.01049047,0.01177829,0.001947912,0.02496406,0.03015987,0.1723089],"genre_scores_gemma":[0.610495,0.0126544,0.1942974,0.00691243,0.0004939313,0.001586,0.01467232,0.002707582,0.1561809],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007203783,"threshold_uncertainty_score":0.02409905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003875129772371877,"score_gpt":0.2785003907109402,"score_spread":0.2746252609385683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}