{"id":"W2627165680","doi":"10.14740/cmmr.v1i1.13","title":"Advances in Molecular Perspectives of Tumor-Initiating Cells on Cancer Therapy","year":2017,"lang":"en","type":"article","venue":"Cellular and Molecular Medicine Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Cancer stem cell; CD44; Homeobox protein NANOG; Wnt signaling pathway; SOX2; Cancer research; Cancer; Biology; Stem cell; Cancer cell; Tumor initiation; Carcinogenesis; Induced pluripotent stem cell; Cell; Cell biology; Embryonic stem cell; Signal transduction; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001413578,0.0005891144,0.0007689543,0.001330343,0.0003492526,0.001535033,0.0006666927,0.001360137,0.005785137],"category_scores_gemma":[0.0009815281,0.0002145628,0.0006183733,0.0009906919,0.001191061,0.001979005,0.0009925583,0.003326662,0.002130954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001078723,"about_ca_system_score_gemma":0.0009518284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004596018,"about_ca_topic_score_gemma":0.0007075678,"domain_scores_codex":[0.9994276,0.0001685632,0.00003339194,0.0000999862,0.0002023309,0.00006822259],"domain_scores_gemma":[0.9992523,0.0003465211,0.0000584378,0.00005668676,0.0001953629,0.00009069774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0003988782,0.00042002,0.001140733,0.005087669,0.00009429725,0.0008200601,0.0004542952,0.001424758,0.06613971,0.1485946,0.03853471,0.7368903],"study_design_scores_gemma":[0.00004930202,0.0005391259,0.001533565,0.0006655751,0.00009750403,0.001763813,0.0001730394,0.001198205,0.02648848,0.03549089,0.9319549,0.00004559396],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007490167,0.9365953,0.01134908,0.01732636,0.002576659,0.00004357715,0.0001438364,0.0001454195,0.02432963],"genre_scores_gemma":[0.06770236,0.9054586,0.008654349,0.004743087,0.003823163,0.00007657275,0.0002227615,0.00005601519,0.00926317],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005785137,"threshold_uncertainty_score":0.01935321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.061045427303164,"score_gpt":0.4202505412232775,"score_spread":0.3592051139201135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}