{"id":"W2628498187","doi":"10.1183/13993003.02322-2016","title":"Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin–lysoPA axis in COPD","year":2017,"lang":"en","type":"article","venue":"European Respiratory Journal","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Vetenskapsrådet; Canadian Institutes of Health Research; Stockholms Läns Landsting; Stiftelsen för Strategisk Forskning; Karolinska Institutet; Hjärt-Lungfonden; AFA Försäkring; VINNOVA; Stiftelsen för Strategisk Forskning; AstraZeneca","keywords":"COPD; Medicine; Oxidative stress; Internal medicine; Metabolomics; Lung; Disease; Gastroenterology; Physiology; Endocrinology; Bioinformatics; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004111947,0.00023744,0.0008402165,0.0005146427,0.0005685771,0.0002824742,0.0006370535,0.00005387797,0.0002239718],"category_scores_gemma":[0.00182029,0.0001618705,0.0003537809,0.0003966191,0.001177158,0.0003286038,0.0003937268,0.0007915435,0.00001560072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001436895,"about_ca_system_score_gemma":0.0002522113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009294273,"about_ca_topic_score_gemma":0.0001751073,"domain_scores_codex":[0.9958782,0.001913173,0.0007234587,0.0003547402,0.0007521901,0.0003782958],"domain_scores_gemma":[0.9974211,0.0002388228,0.0008581235,0.0008015176,0.0004243127,0.0002561513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00167017,0.0005008679,0.9652907,0.0001733572,0.006891069,0.002085266,0.001981721,0.0002578298,0.005158731,0.0005715477,0.0004379595,0.01498074],"study_design_scores_gemma":[0.004921383,0.00006544192,0.9893431,0.0001183577,0.001381808,0.00002826472,0.0009114006,0.0003296465,0.001576673,0.0001329705,0.001040015,0.0001509299],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985294,0.007592508,0.00004553515,0.0003719323,0.0001206182,0.0003035719,0.00008870116,0.00001475763,0.006168381],"genre_scores_gemma":[0.9978334,0.0003944082,0.00007530519,0.0001291894,0.0001648753,0.000004229687,0.000006907492,0.00003814515,0.001353506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02405236,"threshold_uncertainty_score":0.6600887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02769490955043037,"score_gpt":0.3062271135462243,"score_spread":0.278532203995794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}