{"id":"W2630376584","doi":"10.1177/0022034517716438","title":"Methyltransferase G9A Regulates Osteogenesis via <i>Twist</i> Gene Repression","year":2017,"lang":"en","type":"article","venue":"Journal of Dental Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; University of British Columbia","funders":"Japan Society for the Promotion of Science; Canada Research Chairs; Deutscher Akademischer Austauschdienst; Michael Smith Health Research BC","keywords":"Mesenchyme; Biology; Neural crest; RUNX2; Cell biology; Ossification; Osteopontin; Chromatin immunoprecipitation; Molecular biology; Transcription factor; Mesenchymal stem cell; Genetics; Gene expression; Endocrinology; Anatomy; Promoter; Gene; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002137696,0.0001119901,0.0001778459,0.000130025,0.0004464628,0.0001478929,0.0006031367,0.000157749,0.00003982085],"category_scores_gemma":[0.000575429,0.00009266901,0.0001812819,0.00006284098,0.0001771205,0.00001675607,0.0002209458,0.0002467227,0.00001006979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002762259,"about_ca_system_score_gemma":0.0001007283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004877568,"about_ca_topic_score_gemma":0.00003207743,"domain_scores_codex":[0.9981647,0.0002564798,0.0003709029,0.0002289122,0.0006947514,0.0002842354],"domain_scores_gemma":[0.9983652,0.00004729303,0.0002325835,0.0006191909,0.0005343133,0.0002014622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002587533,0.00007203543,0.009968182,0.00001030142,0.00005479111,0.00004607669,0.00002040515,0.00003259704,0.966204,0.000004142436,0.0002580084,0.02307067],"study_design_scores_gemma":[0.0006179712,0.0005520352,0.01906756,0.00002802248,0.00001812856,0.00005755247,0.00003554074,0.00002756148,0.9730513,0.0004412272,0.006004246,0.00009883018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910421,0.006228421,0.001372153,0.0001948495,0.0002468138,0.0001090272,0.000007971659,0.000001657929,0.0007969997],"genre_scores_gemma":[0.9938859,0.003615042,0.001221469,0.0000161929,0.0005647716,0.00000314107,0.0000135087,0.00002295857,0.0006569744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02297184,"threshold_uncertainty_score":0.3778933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05691408423701719,"score_gpt":0.4058825813596507,"score_spread":0.3489684971226334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}